Petry N M, Bickel W K
Department of Psychiatry, Substance Abuse Treatment Center, University of Vermont, Burlington 05401, USA.
Drug Alcohol Depend. 2000 Feb 1;58(1-2):27-33. doi: 10.1016/s0376-8716(99)00058-7.
The purpose of this study was to evaluate gender differences in hostility and the role of hostility in predicting early treatment termination of opioid-dependent outpatients. Demographic characteristics and Addiction Severity Index (ASI) ratings were collected from 104 patients (68 males and 36 females) at intake to a buprenorphine treatment program. Hostility was assessed using the Buss-Durkee Hostility Scale. Compared to male opioid-dependent patients, females scored significantly higher on this scale. Early treatment termination was defined as remaining in treatment < 30 days, and 13% percent of males and 25% of females were classified as early terminators. Stepwise logistic regression identified predictors of early treatment termination. Severity of legal and employment problems and the interaction between hostility and gender predicted early treatment termination status. Patients with less severe legal problems and patients with greater employment problems were more likely to terminate early from treatment. Higher levels of hostility predicted early treatment termination of female patients, but hostility levels were not associated with treatment termination in male patients. Results from this study show that female heroin addicts have high levels of hostility and suggest that hostility may be an important predictor of premature discharge from opioid substitution programs, especially among women.
本研究的目的是评估敌意方面的性别差异以及敌意在预测阿片类药物依赖门诊患者早期治疗终止中的作用。在丁丙诺啡治疗项目入组时，收集了104例患者（68例男性和36例女性）的人口统计学特征及成瘾严重程度指数（ASI）评分。使用布斯-杜克敌意量表评估敌意程度。与男性阿片类药物依赖患者相比，女性在该量表上的得分显著更高。早期治疗终止定义为治疗时间少于30天，13%的男性和25%的女性被归类为早期终止治疗者。逐步逻辑回归分析确定了早期治疗终止的预测因素。法律和就业问题的严重程度以及敌意与性别的相互作用预测了早期治疗终止状态。法律问题不太严重的患者和就业问题较大的患者更有可能早期终止治疗。较高的敌意程度预测了女性患者的早期治疗终止，但敌意程度与男性患者的治疗终止无关。本研究结果表明，女性海洛因成瘾者敌意程度较高，提示敌意可能是阿片类药物替代治疗项目提前出院的重要预测因素，尤其是在女性中。
