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巴尔的摩市两个基层康复项目中丁丙诺啡治疗阿片类药物依赖成功的预测因素。

Predictors of buprenorphine treatment success of opioid dependence in two Baltimore City grassroots recovery programs.

作者信息

Damian April Joy, Mendelson Tamar, Agus Deborah

机构信息

Johns Hopkins Bloomberg School of Public Health, Department of Mental Health, 624 North Broadway Street, Room 798, Baltimore, MD 21205, United States.

Johns Hopkins Bloomberg School of Public Health, Department of Mental Health, 624 North Broadway Street, Room 853, Baltimore, MD 21205, United States.

出版信息

Addict Behav. 2017 Oct;73:129-132. doi: 10.1016/j.addbeh.2017.05.010. Epub 2017 May 10.

Abstract

INTRODUCTION

Despite evidence for the efficacy of buprenorphine treatment in primary care, few studies have identified factors associated with treatment success, nor have such factors been evaluated in community settings. Identifying correlates of treatment success can facilitate the development of treatment models tailored for distinct populations, including low-income communities of color. The current study examined client-level socio-demographic factors associated with treatment success in community-based buprenorphine programs serving vulnerable populations.

METHODS

Data were abstracted from client records for participants (N=445) who met DSM-IV criteria for opioid dependence and sought treatment at one of Behavioral Health Leadership Institute's two community-based recovery programs in Baltimore City from 2010 to 2015. Logistic regression estimated the odds ratios of treatment success (defined as retention in treatment for ≥90days) by sociodemographic predictors including age, race, gender, housing, legal issues and incarceration.

RESULTS

The odds of being retained in treatment ≥90days increased with age (5% increase with each year of age; p<0.001), adjusting for other sociodemographic factors. Clients who reported unstable housing had a 41% decreased odds of remaining in treatment for 90 or more days compared to clients who lived independently at intake. Treatment success did not significantly differ by several other client-level characteristics including gender, race, employment, legal issues and incarceration.

CONCLUSIONS

In vulnerable populations, the age factor appears sufficiently significant to justify creating models formulated for younger populations. The data also support attention to housing needs for people in treatment. Findings from this paper can inform future research and program development.

摘要

引言

尽管有证据表明丁丙诺啡治疗在初级保健中具有疗效,但很少有研究确定与治疗成功相关的因素,而且在社区环境中也未对这些因素进行评估。确定治疗成功的相关因素有助于开发针对不同人群(包括低收入有色人种社区)量身定制的治疗模式。本研究调查了在为弱势群体服务的社区丁丙诺啡项目中与治疗成功相关的个体层面社会人口学因素。

方法

数据取自符合阿片类药物依赖DSM-IV标准并于2010年至2015年期间在巴尔的摩市行为健康领导力研究所的两个社区康复项目之一寻求治疗的参与者(N = 445)的客户记录。逻辑回归通过社会人口学预测因素(包括年龄、种族、性别、住房、法律问题和监禁情况)估计治疗成功(定义为治疗持续≥90天)的优势比。

结果

在调整其他社会人口学因素后,治疗持续≥90天的几率随年龄增加而增加(年龄每增加一岁增加5%;p < 0.001)。报告住房不稳定的客户与入院时独立生活的客户相比,治疗90天或更长时间的几率降低了41%。治疗成功在其他几个个体层面特征(包括性别、种族、就业、法律问题和监禁情况)上没有显著差异。

结论

在弱势群体中,年龄因素似乎足够显著,足以证明为年轻人群体制定治疗模式是合理的。数据还支持关注治疗人群的住房需求。本文的研究结果可为未来的研究和项目开发提供参考。

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