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睾丸存在“消退”现象的性腺外生殖细胞肿瘤

[Extragonadal germ cell tumor with "burned-out" phenomenon in the testis].

作者信息

Ojea Calvo A, Rodríguez Alonso A, Pérez García D, Domínguez Freire F, Alonso Rodrigo A, Rodríguez Iglesias B, Benavente Delgado J, Barros Rodríguez J M, Fiaño Valverde C, Nogueira March J L

机构信息

Servicio de Urología, Hospital Xeral de Vigo.

出版信息

Actas Urol Esp. 1999 Nov-Dec;23(10):880-4. doi: 10.1016/s0210-4806(99)72389-2.

DOI:10.1016/s0210-4806(99)72389-2
PMID:10670132
Abstract

The "burned-out" phenomenon in germ-cell neoplasias is defined by the presence of an extragonadal germ-cell tumour with no tumour at the testis level where a series of distinctive histological lesions can be detected indicative of the earlier presence of an already disappeared testicle tumoration. Extragonadal germ-cell tumours with "burned-out" phenomenon show better evolution than their primary counterparts and are treated similarly to primary tumours of the testis. Currently, in the presence of retroperitoneal tumoration, a scrotal ultrasound study with high frequency transducers can lead to a suspected picture of tumoral involution. This paper contributes one retroperitoneal seminoma with "burned-out" phenomenon in the homolateral testis in a 35-year old patient. Available clinical and radiological criteria were enough to reach a suspected diagnosis. Homolateral orchiectomy and biopsy of retroperitoneal tumoration were performed, rounding treatment up with polychemotherapy. Evolution was good with immediate complete response.

摘要

生殖细胞肿瘤中的“消退”现象定义为存在性腺外生殖细胞肿瘤,而睾丸水平无肿瘤,在此可检测到一系列独特的组织学病变,提示先前存在现已消失的睾丸肿瘤。伴有“消退”现象的性腺外生殖细胞肿瘤比其原发性对应肿瘤具有更好的病程,其治疗方式与睾丸原发性肿瘤相似。目前,在存在腹膜后肿瘤的情况下,使用高频探头进行阴囊超声检查可得出肿瘤消退的可疑图像。本文报道了一名35岁患者,其腹膜后精原细胞瘤伴有同侧睾丸“消退”现象。现有的临床和放射学标准足以做出可疑诊断。进行了同侧睾丸切除术和腹膜后肿瘤活检,并辅以多药化疗完成治疗。病情进展良好,立即获得完全缓解。

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[Extragonadal germ cell tumor with "burned-out" phenomenon in the testis].睾丸存在“消退”现象的性腺外生殖细胞肿瘤
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A massive retroperitoneal mature teratoma from a "burned-out" testicular teratoma and seminoma.一例源自“消退型”睾丸畸胎瘤和精原细胞瘤的巨大腹膜后成熟畸胎瘤。
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2
'Burned-out' syndrome of testicular teratoma: A case report.睾丸畸胎瘤“消退”综合征:一例报告
Mol Clin Oncol. 2021 Dec;15(6):262. doi: 10.3892/mco.2021.2424. Epub 2021 Oct 22.
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Burned-Out Testicular Cancer: Really a Different History?消退型睾丸癌:真的有不同的病史吗?
Case Rep Oncol. 2017 Sep 20;10(3):846-850. doi: 10.1159/000480493. eCollection 2017 Sep-Dec.
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"Burned out" testicular seminoma presenting as a primary gastric malignancy.表现为原发性胃恶性肿瘤的“消退型”睾丸精原细胞瘤。
Int J Clin Oncol. 2009 Feb;14(1):74-7. doi: 10.1007/s10147-008-0804-0. Epub 2009 Feb 20.
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Gastrointestinal bleeding as the first manifestation of a burned-out tumour of the testis.
Clin Transl Oncol. 2005 Nov;7(10):458-63. doi: 10.1007/BF02716597.