Mesa Hector, Rawal Ajay, Rezcallah Anthony, Iwamoto Carlos, Niehans Gloria A, Druck Paul, Gupta Pankaj
Department of Pathology 113, VA Medical Center, Minneapolis, MN 55417, USA.
Int J Clin Oncol. 2009 Feb;14(1):74-7. doi: 10.1007/s10147-008-0804-0. Epub 2009 Feb 20.
In contrast to primary gastric adenocarcinomas, germ cell tumors are potentially curable even when metastatic. It is therefore essential for clinicians and pathologists to be aware of the spectrum of unusual manifestations of germ cell malignancies. Here we report on a 55-year-old man who presented with clinical and endoscopic features indicative of a primary gastric carcinoma. Surprisingly, the ulcerative mucosal lesion was found to be due to a metastasis from an occult, "burned-out" testicular seminoma. This case describes the radiological and pathological features that helped differentiate this rare situation from the much more common gastric adenocarcinoma, and extends the diagnostic possibilities that must be considered in patients presenting with gastric ulcers.
与原发性胃腺癌不同，生殖细胞肿瘤即使发生转移也有治愈的可能。因此，临床医生和病理学家必须了解生殖细胞恶性肿瘤的一系列不寻常表现。在此，我们报告一名55岁男性，其临床和内镜特征提示原发性胃癌。令人惊讶的是，溃疡性黏膜病变被发现是由隐匿性、“消退型”睾丸精原细胞瘤转移所致。本病例描述了有助于将这种罕见情况与更为常见的胃腺癌区分开来的放射学和病理学特征，并扩展了胃溃疡患者必须考虑的诊断可能性。
