Weber O, Hubert J, Grignon Y, Mangin P
Service d'Urologie, CHU de Brabois, Nancy.
Prog Urol. 1996 Apr;6(2):278-81.
Metastatic testicular germ cell tumours with complete involution of the primary site, or "burned-out tumour", constitute a classical but rare entity, whether the initial cell type is seminomatous or non-seminomatous. The authors report one case of this type of tumour. The diagnosis is primarily based on ultrasonography, indicating the need for orchidectomy in the presence of an anomaly, followed by histology, revealing a fibrous scar with no tumour cells. Aetiopathogenic hypotheses are divided between ischaemic and immunological theories. Scrotal ultrasonography and tumour marker assays should be performed systematically in the presence of retroperitoneal adenopathy with normal testicular clinical examination.
原发部位完全消退的转移性睾丸生殖细胞肿瘤,即“消退型肿瘤”,无论初始细胞类型是精原细胞瘤还是非精原细胞瘤,都是一种典型但罕见的实体。作者报告了1例这种类型的肿瘤。诊断主要基于超声检查,提示存在异常时需要进行睾丸切除术,随后进行组织学检查,结果显示为无肿瘤细胞的纤维瘢痕。病因假说分为缺血性和免疫性理论。在睾丸临床检查正常但存在腹膜后淋巴结肿大的情况下,应系统地进行阴囊超声检查和肿瘤标志物检测。