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大动脉D型转位的动脉调转术:利用电影磁共振成像和相移速度映射对血流动力学变化进行中期定量评估——初步经验

Arterial switch procedure for D-transposition of the great arteries: quantitative midterm evaluation of hemodynamic changes with cine MR imaging and phase-shift velocity mapping-initial experience.

作者信息

Gutberlet M, Boeckel T, Hosten N, Vogel M, Kühne T, Oellinger H, Ehrenstein T, Venz S, Hetzer R, Bein G, Felix R

机构信息

Department of Radiology, Charité, Campus Virchow-Klinikum, Medizinische Fakultät der Humboldt-Universität, Augustenburger Platz 1, 13353 Berlin, Germany.

出版信息

Radiology. 2000 Feb;214(2):467-75. doi: 10.1148/radiology.214.2.r00fe45467.

Abstract

PURPOSE

To evaluate cine magnetic resonance (MR) imaging and phase-shift velocity mapping for assessment of the hemodynamic relevance of stenotic segments or specific hemodynamic changes in the great vessels after an arterial switch procedure for correction of D-transposition of the great arteries.

MATERIALS AND METHODS

Twenty consecutive patients (age range, 2-17 years) with an acoustic window that was insufficient for Doppler transthoracic echocardiography were included in the study. Flow and diameter measurements of the pulmonary arterial trunk and its primary branches were performed with phase-shift velocity mapping and cine MR imaging.

RESULTS

There were good correlations between pressure gradients in the pulmonary arteries estimated with MR imaging and those measured with Doppler echocardiography (r = 0.83, n = 15) and cardiac catheterization (r = 0.90, n = 13). Cine MR imaging revealed that the diameters of the right and left pulmonary arteries decreased with the expansion of the aorta during systole, which increased the peak velocity. This temporary stenosis was more severe in the right than in the left pulmonary artery and was accompanied by a significantly (P <.05) lower volume flow in the right artery.

CONCLUSION

The anatomic situation after arterial switch repair tended to produce temporary stenoses in the primary pulmonary arterial branches, with significant changes in hemodynamics. These changes may affect the long-term outcome and go undetected with other imaging modalities.

摘要

目的

评估电影磁共振(MR)成像和相移速度映射,以评估在大动脉调转术矫正大动脉D型转位后,狭窄节段的血流动力学相关性或大血管中特定的血流动力学变化。

材料与方法

本研究纳入了连续20例患者(年龄范围2至17岁),这些患者的声窗不足以进行多普勒经胸超声心动图检查。使用相移速度映射和电影MR成像对肺动脉主干及其主要分支进行血流和直径测量。

结果

MR成像估计的肺动脉压力梯度与多普勒超声心动图测量的压力梯度之间存在良好的相关性(r = 0.83,n = 15),与心导管检查测量的压力梯度之间也存在良好的相关性(r = 0.90,n = 13)。电影MR成像显示,在收缩期,随着主动脉的扩张,右肺动脉和左肺动脉的直径减小,这增加了峰值速度。这种暂时性狭窄在右肺动脉比左肺动脉更严重,并且右肺动脉的血流量显著降低(P <.05)。

结论

大动脉调转修复术后的解剖情况倾向于在主要肺动脉分支中产生暂时性狭窄,并伴有血流动力学的显著变化。这些变化可能会影响长期预后,而其他成像方式可能无法检测到这些变化。

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