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弥漫性乳腺癌中胰岛素样生长因子II升高导致的严重低血糖症。

Severe hypoglycaemia caused by raised insulin-like growth factor II in disseminated breast cancer.

作者信息

Bessell E M, Selby C, Ellis I O

机构信息

Department of Clinical Oncology, Nottingham City Hospital, UK.

出版信息

J Clin Pathol. 1999 Oct;52(10):780-1. doi: 10.1136/jcp.52.10.780.

DOI:10.1136/jcp.52.10.780
PMID:10674040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC501577/
Abstract

A 60 year old woman with disseminated ductal carcinoma of the breast developed non-islet cell tumour induced hypoglycaemia (NICTH). The concentrations of the two insulin-like growth factors, IGF-I and IGF-II, were < 2 nmol/l and 94.1 nmol/l, respectively. The IGF-II to IGF-I ratio was > 47 (normal < 10). Insulin (< 3 mu/l) and C peptide (< 100 pmol/l) were both undetectable.

摘要

一名60岁患有弥漫性乳腺导管癌的女性发生了非胰岛细胞瘤所致低血糖症（NICTH）。两种胰岛素样生长因子，即IGF-I和IGF-II的浓度分别<2 nmol/l和94.1 nmol/l。IGF-II与IGF-I的比值>47（正常<10）。胰岛素（<3 mu/l）和C肽（<100 pmol/l）均检测不到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e078/501577/8e138c5fda4e/jclinpath00283-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e078/501577/8e138c5fda4e/jclinpath00283-0069-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e078/501577/8e138c5fda4e/jclinpath00283-0069-a.jpg

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