Teirney R, Arachchi G J, Fraser I S
Sydney Centre for Reproductive Health Research, Family Planning NSW, Ashfield, Australia.
Obstet Gynecol. 2000 Feb;95(2):251-4. doi: 10.1016/s0029-7844(99)00527-x.
To examine objectively the long-term efficacy of endometrial ablation for menorrhagia.
Thirty-nine women with menorrhagia due to ovulatory dysfunctional bleeding treated previously by rollerball ablation were followed up 5-6 years later. Menstrual blood in sanitary towels was measured with the alkaline hematin technique in 26 women who were still premenopausal and in whom menstrual blood loss had been measured before and immediately after the original ablation.
Mean (+/- standard deviation [SD]) menstrual blood loss (per menstrual period) was reduced from 90 mL +/- 14.4 before ablation to 3.8 mL +/- 2.1 at 3 months, 1.8 mL +/- 1.0 at 6 months, and 3.3 mL +/- 1.3 at 5-6 years after ablation. In women who were still menstruating, the mean hemoglobin concentration rose significantly from 126 to 135 g/L (P = .022).
Rollerball endometrial ablation is a highly effective long-term therapy for carefully selected women with menorrhagia due to ovulatory dysfunctional uterine bleeding.
客观评估子宫内膜切除术治疗月经过多的长期疗效。
对39例曾接受滚球式子宫内膜切除术治疗排卵性功能失调性子宫出血所致月经过多的女性进行了5至6年的随访。采用碱性正铁血红素技术对26例仍处于绝经前且在初次切除术前及术后立即测量过月经量的女性的卫生巾上的月经量进行了测量。
平均（±标准差[SD]）月经量（每次月经周期）从切除术前的90 mL±14.4减少至术后3个月时的3.8 mL±2.1、6个月时的1.8 mL±1.0以及5至6年时的3.3 mL±1.3。仍在月经的女性中，平均血红蛋白浓度从126显著升至135 g/L（P = 0.022）。
对于精心挑选的排卵性功能失调性子宫出血所致月经过多的女性，滚球式子宫内膜切除术是一种高效的长期治疗方法。
