Ng M, Yanofsky M F
Department of Biology, University of California at San Diego, La Jolla, 92093-0116, USA.
Curr Opin Plant Biol. 2000 Feb;3(1):47-52. doi: 10.1016/s1369-5266(99)00036-9.
The ABC model of flower development represents a milestone in explaining how the fate of emerging floral organ primordia is specified. This model states that organ identity is specified by different combinations of the activities of the A, B and C class homeotic genes. In spite of the remarkable simplicity of this model, the complex regulatory interactions that establish the initial pattern of A, B and C gene activity have yet to be fully explained. It has been shown that the LEAFY gene functions early to promote flower meristem identity, and that it is subsequently required for the normal expression of the ABC genes. Recently, LEAFY has been identified as an immediate upstream regulator of the floral homeotic genes, thus opening up an avenue to examine the transcriptional interactions that underlie floral patterning.
花发育的ABC模型是解释新出现的花器官原基命运如何被确定的一个里程碑。该模型指出，器官特性是由A、B和C类同源异型基因活性的不同组合所确定的。尽管这个模型非常简单，但建立A、B和C基因活性初始模式的复杂调控相互作用尚未得到充分解释。研究表明，LEAFY基因早期发挥作用促进花分生组织特性，并且随后是ABC基因正常表达所必需的。最近，LEAFY已被确定为花同源异型基因的直接上游调节因子，从而为研究花形态建成背后的转录相互作用开辟了一条途径。
