Brockwell D J, Smith D A, Radford S E
School of Biochemistry and Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.
Curr Opin Struct Biol. 2000 Feb;10(1):16-25. doi: 10.1016/s0959-440x(99)00043-3.
During the past year, advances in our understanding of folding mechanisms have been made through detailed experimental and theoretical studies of a number of proteins. The development of new methods has allowed the earliest events in folding to be probed and the measurement of folding at the level of individual molecules is now possible, opening the door to exciting new experiments.
在过去的一年里，通过对多种蛋白质进行详细的实验和理论研究，我们对折叠机制的理解取得了进展。新方法的发展使得折叠过程中最早发生的事件得以探究，并且现在已经能够在单个分子水平上测量折叠情况，这为开展令人兴奋的新实验打开了大门。
