Miranker A D, Dobson C M
New Chemistry Laboratory, Oxford Centre for Molecular Sciences, University of Oxford, UK.
Curr Opin Struct Biol. 1996 Feb;6(1):31-42. doi: 10.1016/s0959-440x(96)80092-3.
The folding of a polypeptide chain is associated both with compactness and cooperativity within local and global regions of the protein structure, and with the formation of the native-like molecular architecture. Recent experiments shed light on these issues and their relationships to the pathways of protein folding.
多肽链的折叠与蛋白质结构局部和整体区域内的紧密性和协同性相关，也与类天然分子结构的形成有关。最近的实验揭示了这些问题以及它们与蛋白质折叠途径的关系。
