von Bubnoff N, Sandherr M, Schneller F, Peschel C
Medizinische Klinik und Poliklinik der Technischen Universität, Munich, Germany.
Am J Clin Oncol. 2000 Feb;23(1):74-7. doi: 10.1097/00000421-200002000-00021.
We present a case of a 52-year-old woman with thrombotic thrombocytopenic purpura associated with progressive metastatic adenocarcinoma of the breast. The patient received plasma exchange therapy. Thrombocytopenic purpura resolved 2 months after discontinuation of plasma exchange while the patient received chemotherapy. After 3 more months, a fulminant relapse of the thrombocytopenic purpura developed, and there were signs of tumor progression. She died despite adequate treatment. We conclude that effective treatment of the underlying tumor can be crucial to control cancer-associated thrombocytopenic purpura.
我们报告一例52岁女性，患有血栓性血小板减少性紫癜，与乳腺进行性转移性腺癌相关。该患者接受了血浆置换疗法。在停止血浆置换且患者接受化疗后，血小板减少性紫癜在2个月后得到缓解。又过了3个月，血小板减少性紫癜出现暴发性复发，且有肿瘤进展的迹象。尽管进行了充分治疗，她仍死亡。我们得出结论，有效治疗潜在肿瘤对于控制癌症相关的血小板减少性紫癜可能至关重要。
