大鼠胎儿肝脏糖原的周转
Turnover of liver glycogen in the rat foetus.
作者信息
Gilbert M, Bourbon J
出版信息
Biochem J. 1978 Dec 15;176(3):785-9. doi: 10.1042/bj1760785.
Abstract
Incorporation and release of the radioactivity in the liver glycogen of 18.5- and 19.5-day-old rat foetuses were studied after intravenous injection of E11-14C]glycerol. Incorporation occurred during 1 h after injection of the radioactive tracer to the foetus; then, the incorporated radioactivity decreased. Glycogen content in the liver, and glycogen phosphorylase and glycogen synthase were not modified during the experiment. It is therefore postulated that a physiological turnover of glycogen exists in the liver of the rat foetus.
摘要
在静脉注射[E11-14C]甘油后，研究了18.5日龄和19.5日龄大鼠胎儿肝脏糖原中放射性的掺入和释放情况。放射性示踪剂注射到胎儿体内后1小时内发生了掺入；然后，掺入的放射性降低。实验过程中肝脏中的糖原含量、糖原磷酸化酶和糖原合酶均未发生改变。因此推测大鼠胎儿肝脏中存在糖原的生理性周转。
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