Paglini G, Peris L, Mascotti F, Quiroga S, Caceres A
Instituto Investigacion Medica Mercedes y Martin Ferreyra (INIMEC-CONICET), Cordoba, Argentina.
Neurochem Res. 2000 Jan;25(1):37-42. doi: 10.1023/a:1007531230651.
Tau protein is a predominantly neuronal microtubule-associated protein that is enriched in axons and is capable of promoting microtubule assembly and stabilization. In the present article we review some of the key experiments directed to obtain insights about tau protein function in developing neurons. Aspects related to whether or not tau has essential, unique, or complementary functions during axonal formation are discussed.
tau蛋白是一种主要存在于神经元中的微管相关蛋白，在轴突中含量丰富，能够促进微管组装和稳定。在本文中，我们回顾了一些关键实验，旨在深入了解tau蛋白在发育中神经元的功能。讨论了与tau在轴突形成过程中是否具有基本、独特或互补功能相关的问题。
