Banerjee H, Verma M
Department of Biology, Long Island University, Brooklyn Campus, New York, 11201-8423, USA.
Plasmid. 2000 Mar;43(2):181-3. doi: 10.1006/plas.1999.1452.
Certain yeast strains secrete a protein toxin, which inhibits the growth of sensitive pathogens and yeasts. Studies have shown that production of the toxin is dependent on presence of linear, double-stranded DNA plasmids in the killer yeasts. In the yeast Pichia pastoris, two linear double-stranded DNA plasmids have been identified. In the present study, the search for toxin-producing capability in P. pastoris has been conducted. No killer activity could be detected when 14 different indicator strains were tested.
某些酵母菌株会分泌一种蛋白质毒素，这种毒素会抑制敏感病原体和酵母的生长。研究表明，毒素的产生取决于杀伤酵母中线性双链DNA质粒的存在。在巴斯德毕赤酵母中，已鉴定出两种线性双链DNA质粒。在本研究中，对巴斯德毕赤酵母产生毒素的能力进行了探索。当测试14种不同的指示菌株时，未检测到杀伤活性。
