Piagnerelli M, Lejeune P, Vanhaeverbeek M
Service de Médecine Interne, C.H.U. André Vésale, Université Libre de Bruxelles, Montigny-le-Tilleul, Belgique.
Acta Clin Belg. 1999 Dec;54(6):351-6. doi: 10.1080/17843286.1999.11754259.
Ethylene glycol intoxication is a rare but dangerous type of poisoning. It causes a severe acidosis with high anion and osmolal gaps. Clinical manifestations of the ethylene glycol intoxication can be divided in three phases: a neurologic stage, with hallucinations, stupor and coma; the second stage is cardiovascular with cardiac failure. Renal failure characterizes the third stage, due to acute tubular necrosis. After aggressive gastric emptying, the main treatment is ethanol or 4-methypyrazole, which can be given either orally or intravenous, with supportive measures for all symptoms or diseased organ.
乙二醇中毒是一种罕见但危险的中毒类型。它会导致严重的酸中毒，伴有高阴离子间隙和渗透压间隙。乙二醇中毒的临床表现可分为三个阶段：神经学阶段，出现幻觉、木僵和昏迷；第二阶段是心血管阶段，表现为心力衰竭。肾衰竭是第三阶段的特征，由急性肾小管坏死引起。在积极进行洗胃后，主要治疗方法是使用乙醇或4-甲基吡唑，可口服或静脉给药，并针对所有症状或患病器官采取支持性措施。
