Prinz J, Böll B, von Bergwelt-Baildon M, Burst V, Becker J U, Carvalho-Fiel D, Shimabukuro-Vornhagen A, Kochanek M
Klinik I für Innere Medizin, Universitätsklinikum Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Medizinische Klinik und Poliklinik III, Klinikum der Universität München, München, Deutschland.
Med Klin Intensivmed Notfmed. 2019 Mar;114(2):159-163. doi: 10.1007/s00063-018-0439-5. Epub 2018 Apr 12.
Ethylene glycol poisoning of incidental or suicidal intention can cause life-threatening metabolic acidosis, diverse secondary damage, and even lead to death. Beside hemodialysis effective therapy consists of the administration of fomepizole and ethanol. We describe a patient after repeated ethylene glycol poisoning with high anion gap metabolic acidosis and acute renal failure. Using hemodialysis, with dialysate containing a specific amount of ethanol, and intravenous ethanol administration we were able to prevent severe secondary organ damage.
意外或自杀性乙二醇中毒可导致危及生命的代谢性酸中毒、多种继发性损害,甚至死亡。除血液透析外,有效的治疗方法包括使用甲吡唑和乙醇。我们描述了一名反复发生乙二醇中毒并伴有高阴离子间隙代谢性酸中毒和急性肾衰竭的患者。通过使用含有特定量乙醇的透析液进行血液透析以及静脉注射乙醇,我们成功预防了严重的继发性器官损害。