Seiler C A, Brügger L, Forssmann U, Baer H U, Büchler M W
Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, Switzerland.
Surgery. 2000 Feb;127(2):178-84. doi: 10.1067/msy.2000.101583.
Peritonitis is, even today, a significant source of death and complications. The objective of this study was to determine the morbidity and mortality rates, the incidence of reoperations, and the need for additional treatment strategies (on demand) in patients with diffuse peritonitis.
Prospective analysis including all patients (n = 258) with diffuse peritonitis admitted to our surgical service between November 1993 and April 1998 who underwent a uniform surgical treatment concept of peritonitis including early intervention, source control, and extensive intraoperative lavage.
The 258 patients with diffuse peritonitis averaged a mean Mannheim Peritonitis Index of 27.1 points (range, 11-43 points). Source control at the initial operation was possible in 230 of the patients (89%), of those, 21 patients (9%) needed reintervention. In 28 patients (11%), source control was not possible at the initial operation. Twenty of these patients (71%) had to undergo additional treatment strategies (on demand) such as continuous lavage and/or laparostomy. Overall 228 of the 258 patients (88%) needed just 1 initial surgical intervention. The overall morbidity rate was 41%; the rate of reoperation was 12%, and the hospital mortality rate was 14%.
A conservative surgical treatment concept supplemented with "extensive" intraoperative lavage reduces the reoperation rate compared with other treatment standards of peritonitis and achieves a low mortality rate in patients with diffuse peritonitis.
即使在今天,腹膜炎仍是死亡和并发症的重要来源。本研究的目的是确定弥漫性腹膜炎患者的发病率和死亡率、再次手术的发生率以及额外治疗策略(按需)的必要性。
前瞻性分析纳入了1993年11月至1998年4月间入住我院外科、接受统一腹膜炎手术治疗理念(包括早期干预、源头控制和广泛术中灌洗)的所有弥漫性腹膜炎患者(n = 258)。
258例弥漫性腹膜炎患者的曼海姆腹膜炎指数平均为27.1分(范围11 - 43分)。230例患者(89%)在初次手术时实现了源头控制,其中21例患者(9%)需要再次干预。28例患者(11%)在初次手术时无法实现源头控制。这些患者中有20例(71%)不得不接受额外的治疗策略(按需),如持续灌洗和/或剖腹造口术。258例患者中总体有228例(88%)仅需1次初次手术干预。总体发病率为41%;再次手术率为12%,医院死亡率为14%。
与其他腹膜炎治疗标准相比,辅以“广泛”术中灌洗的保守手术治疗理念可降低再次手术率,并使弥漫性腹膜炎患者实现低死亡率。