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妊娠与肝硬化

Pregnancy and cirrhosis of the liver.

作者信息

Aggarwal N, Sawnhey H, Suril V, Vasishta K, Jha M, Dhiman R K

机构信息

Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Aust N Z J Obstet Gynaecol. 1999 Nov;39(4):503-6. doi: 10.1111/j.1479-828x.1999.tb03145.x.

DOI:10.1111/j.1479-828x.1999.tb03145.x
PMID:10687776
Abstract

Pregnancy in patients with cirrhosis of the liver is uncommon. We reviewed 9 pregnancies in 7 patients with cirrhosis. One patient conceived within 1 month of diagnosis and in another the disease was diagnosed during the index pregnancy. Four patients has associated portal hypertension and 1 of them conceived after lienorenal shunt. Complications associated with these pregnancies were jaundice (1) jaundice plus ascites (2) and gastrointestinal bleeding (1). In 2 patients endoscopic sclerotherapy was done during the index pregnancy. The incidence of preterm delivery was 50% (4 of 8) and the majority (75%) occurred in pregnancies where associated complications were present. There was 1 maternal death in the postpartum period due to fulminant hepatic failure.

摘要

肝硬化患者怀孕并不常见。我们回顾了7例肝硬化患者的9次妊娠情况。1例患者在确诊后1个月内怀孕,另1例患者在本次妊娠期间被诊断出患有该病。4例患者伴有门静脉高压,其中1例在脾肾分流术后怀孕。这些妊娠相关的并发症包括黄疸(1例)、黄疸加腹水(2例)和胃肠道出血(1例)。2例患者在本次妊娠期间接受了内镜硬化治疗。早产发生率为50%(8例中的4例),大多数(75%)发生在伴有相关并发症的妊娠中。产后有1例产妇因暴发性肝衰竭死亡。

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