Kyle L A, Turner B S
Duke University School of Nursing, Durham, NC 27710, USA.
Neonatal Netw. 1999 Sep;18(6):49-54. doi: 10.1891/0730-0832.18.6.49.
The purpose of this study was to compare saline and heparin flushes in 24-gauge i.v. catheters.
A double-blind experiment in four recorded trials was conducted using a rabbit model. Twenty-four-gauge catheters were placed in both auricle veins, and all catheters were secured in the same manner. Ampicillin was infused into each ear at the same interval, with each ear randomized to receive either the heparin solution or the saline solution.
The subjects were ten white New Zealand rabbits. Data were collected on 76 catheter sites.
Patency for each catheter was measured in hours and evaluated based on presence of warmth, erythema, induration, leakage, or occlusion.
There was no significant difference in the duration of patency of the catheters between the two groups.
本研究旨在比较24号静脉留置针使用生理盐水和肝素封管的效果。
采用兔模型进行四项记录试验的双盲实验。在双耳静脉均置入24号导管，所有导管均以相同方式固定。每隔相同时间向每只耳朵输注氨苄青霉素，每只耳朵随机接受肝素溶液或生理盐水溶液。
实验对象为10只白色新西兰兔。收集了76个导管部位的数据。
测量每个导管的通畅时间（以小时为单位），并根据是否存在发热、红斑、硬结、渗漏或堵塞情况进行评估。
两组导管的通畅持续时间无显著差异。
