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自体角膜缘-结膜移植治疗复发性翼状胬肉

Limbal-conjunctival autograft transplantation for the treatment of recurrent pterygium.

作者信息

Gris O, Güell J L, del Campo Z

机构信息

Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

出版信息

Ophthalmology. 2000 Feb;107(2):270-3. doi: 10.1016/s0161-6420(99)00041-x.

DOI:10.1016/s0161-6420(99)00041-x
PMID:10690823
Abstract

OBJECTIVE

Different investigators have recently emphasized the importance of the limbus and its stem cells in the pathogenesis of the pterygium. In this article we examine the usefulness of limbal-conjunctival autograft transplantation for the treatment of advanced recurrent pterygium.

DESIGN

Prospective noncomparative case series.

PARTICIPANTS

Seven patients with advanced recurrent pterygium. All had previously been treated a minimum of two times by simple excision (two of them with intraoperative mitomycin C).

INTERVENTION

Limbal-conjunctival autograft transplantation after pterygium excision was performed in all cases.

MAIN OUTCOME MEASURES

Pterygium recurrences and complications with a minimal follow-up period of 14 months.

RESULTS

There were no recurrences of pterygial growth beyond the limbal edge. In addition, no significant complications were noted. Only one case of limited pseudopterygium in the donor site and one case of graft retraction were recorded. No further surgical interventions were needed in any case.

CONCLUSIONS

Limbal-conjunctival autograft transplantation is a promising technique for the treatment of advanced recurrent pterygium.

摘要

目的

不同研究者近来强调了角膜缘及其干细胞在翼状胬肉发病机制中的重要性。在本文中,我们探讨角膜缘结膜自体移植术治疗晚期复发性翼状胬肉的有效性。

设计

前瞻性非对照病例系列。

研究对象

7例晚期复发性翼状胬肉患者。所有患者此前均至少接受过两次单纯切除术治疗(其中2例术中使用了丝裂霉素C)。

干预措施

所有病例均在翼状胬肉切除术后行角膜缘结膜自体移植术。

主要观察指标

翼状胬肉复发情况及并发症,最短随访期为14个月。

结果

角膜缘边缘以外未出现翼状胬肉复发。此外,未观察到明显并发症。仅记录到1例供区局限性假性胬肉和1例移植片退缩。所有病例均无需进一步手术干预。

结论

角膜缘结膜自体移植术是治疗晚期复发性翼状胬肉的一种有前景的技术。

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