Pomeranz H D, Lessell S
Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, USA.
Neurology. 2000 Feb 22;54(4):855-9. doi: 10.1212/wnl.54.4.855.
To report the occurrence of palinopsia and polyopia in patients who neither used drugs nor had diseases of the cerebral hemispheres, a group in which these visual symptoms have not been reported.
The patient records in the database of an academic neuro-ophthalmology unit were reviewed.
Seventeen patients were identified in the database with the diagnosis of palinopsia or polyopia, of whom eight had diseases of the cerebral hemispheres, leaving nine patients for analysis. No patients with a history of drug toxicity were identified. In one patient the symptoms presented during an initial episode of demyelinative optic neuritis in the absence of clinical or laboratory evidence of cerebral lesions. In another patient they developed immediately after laser treatment of diabetic macular edema. A third patient developed the symptoms in association with visual loss from Leber's hereditary optic neuropathy. The other six patients were healthy individuals.
Palinopsia and related visual symptoms can occur in otherwise healthy individuals and in patients with disease apparently confined to the eye or the optic nerve.
报告在既未使用药物也无大脑半球疾病的患者中出现的持续性视觉后像和视物显多症，这是一组此前未报告过这些视觉症状的人群。
对一个学术性神经眼科单位数据库中的患者记录进行了回顾。
在数据库中确定了17例诊断为持续性视觉后像或视物显多症的患者，其中8例患有大脑半球疾病，其余9例用于分析。未发现有药物毒性史的患者。1例患者在脱髓鞘性视神经炎初次发作时出现症状，当时无脑部病变的临床或实验室证据。另1例患者在糖尿病性黄斑水肿激光治疗后立即出现这些症状。第3例患者出现这些症状与Leber遗传性视神经病变导致的视力丧失有关。其他6例患者为健康个体。
持续性视觉后像及相关视觉症状可发生于其他方面健康的个体以及疾病明显局限于眼部或视神经的患者。
