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Early B cell defects.早期B细胞缺陷。
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Curr Opin Immunol. 2010 Apr;22(2):161-7. doi: 10.1016/j.coi.2010.01.010. Epub 2010 Feb 9.

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Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect.患有 SNARE 蛋白 SYNTAXIN-11 缺乏症的患者和老鼠存在次级 B 细胞缺陷。
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Response to mRNA COVID-19 vaccination in three XLA patients.三位 XLA 患者对 mRNA COVID-19 疫苗的反应。
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Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.缺氧诱导因子-1α 活性的动态调节对正常 B 细胞发育至关重要。
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Naturally occurring Bruton's tyrosine kinase mutations have no dominant negative effect in an X-linked agammaglobulinaemia cellular model.在X连锁无丙种球蛋白血症细胞模型中,自然发生的布鲁顿酪氨酸激酶突变无显性负效应。
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[Classification and diagnosis of immunodeficiency syndromes].[免疫缺陷综合征的分类与诊断]
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本文引用的文献

1
Agammaglobulinemia.无丙种球蛋白血症
Trans Assoc Am Physicians. 1953;66:200-2.
2
Mutations in Igalpha (CD79a) result in a complete block in B-cell development.免疫球蛋白α(CD79a)的突变会导致B细胞发育完全受阻。
J Clin Invest. 1999 Oct;104(8):1115-21. doi: 10.1172/JCI7696.
3
Atypical X-linked agammaglobulinemia diagnosed in three adults.三名成年人被诊断为非典型X连锁无丙种球蛋白血症。
Intern Med. 1999 Sep;38(9):722-5. doi: 10.2169/internalmedicine.38.722.
4
Activity of pleconaril against enteroviruses.普来可那立对肠道病毒的活性。
Antimicrob Agents Chemother. 1999 Sep;43(9):2109-15. doi: 10.1128/AAC.43.9.2109.
5
Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase.布鲁顿酪氨酸激酶对TFII-I核定位和转录活性的调控
Mol Cell Biol. 1999 Jul;19(7):5014-24. doi: 10.1128/MCB.19.7.5014.
6
Mutations of the human BTK gene coding for bruton tyrosine kinase in X-linked agammaglobulinemia.X连锁无丙种球蛋白血症中编码布鲁顿酪氨酸激酶的人类BTK基因突变。
Hum Mutat. 1999;13(4):280-5. doi: 10.1002/(SICI)1098-1004(1999)13:4<280::AID-HUMU3>3.0.CO;2-L.
7
Unusual mutations in Btk: an insertion, a duplication, an inversion, and four large deletions.布鲁顿酪氨酸激酶(Btk)的罕见突变:一个插入突变、一个重复突变、一个倒位突变和四个大片段缺失。
Clin Immunol. 1999 Jan;90(1):28-37. doi: 10.1006/clim.1998.4629.
8
Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease.宿主防御分子多态性影响慢性肉芽肿病免疫介导并发症的风险。
J Clin Invest. 1998 Dec 15;102(12):2146-55. doi: 10.1172/JCI5084.
9
Functional analysis of peripheral blood B cells in patients with X-linked agammaglobulinemia.X连锁无丙种球蛋白血症患者外周血B细胞的功能分析
J Immunol. 1998 Oct 15;161(8):3925-9.
10
Immunoglobulin replacement treatment by rapid subcutaneous infusion.通过快速皮下输注进行免疫球蛋白替代治疗。
Arch Dis Child. 1998 Jul;79(1):48-51. doi: 10.1136/adc.79.1.48.

Early B cell defects.

作者信息

Gaspar H B, Conley M E

机构信息

Molecular Immunology Unit, Institute of Child Health, University College London, London, UK.

出版信息

Clin Exp Immunol. 2000 Mar;119(3):383-9. doi: 10.1046/j.1365-2249.2000.01192.x.

DOI:10.1046/j.1365-2249.2000.01192.x
PMID:10691907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1905597/
Abstract
摘要