Nakagawa T, Sekizawa K, Nakajoh K, Tanji H, Arai H, Sasaki H
Department of Geriatric Medicine, Tohoku University School of Medicine, Sendai 980-8574 Japan.
J Intern Med. 2000 Feb;247(2):255-9. doi: 10.1046/j.1365-2796.2000.00599.x.
To determine whether patients who have silent cerebral infarction are more likely to develop pneumonia than are controls without silent cerebral infarction.
We examined 269 community-residing participants of the senior day-care centre without history of previous stroke, and then followed them over a two-year period to assess pneumonia. On the basis of computerized tomography scans, they were divided into two groups: no infarction (n = 102) and cerebral hemispheric infarction (n = 167). Cerebral infarcts were further divided into deep and superficial infarcts.
The incidence of pneumonia was significantly higher in subjects with silent cerebral infarction (19.8%) than in controls (4. 9%) (odds ratio, 4.67 [95% CI, 1.87-11.67]; P < 0.01). Deep infarcts were more closely associated with the incidence of pneumonia (29.1%) than superficial infarcts (7.6%) (odds ratio, 5.00 [CI, 1.91-13.08]; P < 0.01).
Elderly subjects with silent cerebral infarction were more likely to develop pneumonia than were controls without silent cerebral infarction. Amongst hemispheric silent cerebral infarcts, those located in the deep brain structures may be an important predictor of the development of pneumonia.
确定无症状性脑梗死患者是否比无无症状性脑梗死的对照组更易发生肺炎。
我们对269名无既往卒中史的社区老年日间护理中心参与者进行了检查，然后对他们进行了为期两年的随访以评估肺炎情况。根据计算机断层扫描结果，他们被分为两组：无梗死组（n = 102）和脑半球梗死组（n = 167）。脑梗死进一步分为深部梗死和浅表梗死。
无症状性脑梗死患者的肺炎发生率（19.8%）显著高于对照组（4.9%）（优势比，4.67 [95% CI，1.87 - 11.67]；P < 0.01）。深部梗死比浅表梗死与肺炎发生率的关联更密切（29.1% 比 7.6%）（优势比，5.00 [CI，1.91 - 13.08]；P < 0.01）。
有无症状性脑梗死的老年患者比无无症状性脑梗死的对照组更易发生肺炎。在半球无症状性脑梗死中，位于深部脑结构的梗死可能是肺炎发生的重要预测因素。
