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核黄素与2,6 - 二氨基 - 9 - 乙基嘌呤复合物的晶体结构：一种表现出电荷转移相互作用的黄素腺嘌呤二核苷酸模型。

Crystal structure of a complex between lumiflavin and 2,6-diamino-9-ethylpurine: a flavin adenine dinucleotide model exhibiting charge-transfer interactions.

作者信息

Scarbrough F E, Shieh H, Voet D

出版信息

Proc Natl Acad Sci U S A. 1976 Nov;73(11):3807-11. doi: 10.1073/pnas.73.11.3807.

DOI:10.1073/pnas.73.11.3807
PMID:1069265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC431218/
Abstract

The x-ray structure of the deep red crystalline complex lumiflavin-2,6-diamino-9-ethylpurine has been determined. The flavin and adenine derivatives form hydrogen-bonded base pairs of the Watson-Crick type. The molecules in the crystal also associate via extensively overlapped flavin/adenine and flavin/flavin stacking interactions in which there are several contacts that are closer than van der Waals distances. This, together with the red color of the crystals, is indicative of the formation of a charge-transfer complex.

摘要

已确定深红色晶体复合物黄素单核苷酸-2,6-二氨基-9-乙基嘌呤的X射线结构。黄素和腺嘌呤衍生物形成沃森-克里克型氢键碱基对。晶体中的分子还通过广泛重叠的黄素/腺嘌呤和黄素/黄素堆积相互作用缔合，其中有几个接触距离比范德华距离更近。这与晶体的红色一起，表明形成了电荷转移复合物。

相似文献

1
Crystal structure of a complex between lumiflavin and 2,6-diamino-9-ethylpurine: a flavin adenine dinucleotide model exhibiting charge-transfer interactions.核黄素与2,6 - 二氨基 - 9 - 乙基嘌呤复合物的晶体结构：一种表现出电荷转移相互作用的黄素腺嘌呤二核苷酸模型。
Proc Natl Acad Sci U S A. 1976 Nov;73(11):3807-11. doi: 10.1073/pnas.73.11.3807.
2
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3
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本文引用的文献

1
HYDROGEN-BONDED DIMERS OF ADENINE AND URACIL DERIVATIVES.腺嘌呤与尿嘧啶衍生物的氢键二聚体
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COENZYME SPECIFICITY OF D-AMINO ACID OXIDASE FOR THE ADENYLATE MOIETY OF FAD.D-氨基酸氧化酶对黄素腺嘌呤二核苷酸（FAD）腺苷酸部分的辅酶特异性
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4
Specific association of riboflavin and adenine derivatives in chloroform solution and the effect of barbiturates on the association.核黄素与腺嘌呤衍生物在氯仿溶液中的特异性缔合以及巴比妥类药物对该缔合的影响。
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Temperature-dependent properties of dinucleoside phosphates.二核苷磷酸的温度依赖性特性。
Biopolymers. 1968;6(2):223-42. doi: 10.1002/bip.1968.360060206.
6
Stereochemistry of nucleic acids and their constituents. X. Solid-state base-stacking patterns in nucleic acid constituents and polynucleotides.核酸及其成分的立体化学。X.核酸成分和多核苷酸中的固态碱基堆积模式。
Biopolymers. 1971;10(1):175-219. doi: 10.1002/bip.360100113.
7
The crystal and molecular structure of an intermolecular complex between riboflavin and an adenosine derivative.核黄素与腺苷衍生物分子间复合物的晶体结构和分子结构
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1151-6. doi: 10.1073/pnas.68.6.1151.
8
The crystal structures of purines, pyrimidines and their intermolecular complexes.嘌呤、嘧啶及其分子间复合物的晶体结构。
Prog Nucleic Acid Res Mol Biol. 1970;10:183-265. doi: 10.1016/s0079-6603(08)60565-6.
9
The effect of pressure on the molecular complex of isoalloxazine and adenine.压力对异咯嗪与腺嘌呤分子复合物的影响。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1264-6. doi: 10.1073/pnas.71.4.1264.
10
Intramolecular hydrogen bonding in flavin adenine dinucleotide.黄素腺嘌呤二核苷酸中的分子内氢键
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4546-50. doi: 10.1073/pnas.71.11.4546.