压力对异咯嗪与腺嘌呤分子复合物的影响。
The effect of pressure on the molecular complex of isoalloxazine and adenine.
作者信息
Weber G, Tanaka F, Okamoto B Y, Drickamer H G
出版信息
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1264-6. doi: 10.1073/pnas.71.4.1264.
Abstract
The effect of pressure to 10 kilobars on the fluorescence characteristics of flavin mononucleotide (FMN), flavin-adenine dinucleotide (FAD), and on complexes of FMN with adenylic acid (AMP), and with I(-) has been studied. The properties measured include peak location, fluorescence yield, and lifetime. From these results the equilibrium constant K and the rate constant k(+) (*) for complex formation were evaluated as a function of pressure. The pressure dependence of these coefficients shows that the volume of the system decreases upon complex formation and that there is an expansion upon formation of the activated complex (DeltaVdouble dagger is positive). The implications of these results for protein denaturation are mentioned.
摘要
研究了10千巴压力对黄素单核苷酸（FMN）、黄素腺嘌呤二核苷酸（FAD）以及FMN与腺苷酸（AMP）和I⁻形成的复合物荧光特性的影响。所测量的性质包括峰位置、荧光产率和寿命。根据这些结果，评估了作为压力函数的复合物形成的平衡常数K和速率常数k(+) (*)。这些系数对压力的依赖性表明，复合物形成时系统体积减小，而活化复合物形成时体积膨胀（ΔV双匕首为正）。文中提到了这些结果对蛋白质变性的影响。
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本文引用的文献
1
THE FLAVIN COMPOSITION OF PIG HEART MUSCLE PREPARATIONS.猪心肌制剂的黄素成分。
Biochem Z. 1963;338:474-84.
2
Volume changes in ovalbumin and bovine serum albumin on adding acid.添加酸时卵清蛋白和牛血清白蛋白的体积变化。
Biochim Biophys Acta. 1958 Apr;28(1):87-91. doi: 10.1016/0006-3002(58)90431-1.
3
Reversible pressure--temperature denaturation of chymotrypsinogen.
Biochemistry. 1971 Jun 22;10(13):2436-42. doi: 10.1021/bi00789a002.
4
Thermodynamics of protein denaturation. Effect of pressu on the denaturation of ribonuclease A.蛋白质变性的热力学。压力对核糖核酸酶A变性的影响。
Biochemistry. 1970 Feb 17;9(4):1038-47. doi: 10.1021/bi00806a045.
5
Pressure denaturation of metmyoglobin.高铁肌红蛋白的压力变性
Biochemistry. 1973 Oct 9;12(21):4217-28. doi: 10.1021/bi00745a028.
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