Horváth O P, Lukács L, Cseke L
First Department of Surgery, University Medical School of Pécs, Hungary.
Recent Results Cancer Res. 2000;155:161-73. doi: 10.1007/978-3-642-59600-1_17.
Chronologically, complications can be classified as intraoperative, early, and late. The authors analyze complications according to this classification on the basis of more than 400 esophageal operations and related literary data. As regards intraoperative complications, they deal only with those occurring at transhiatal esophagectomy (e.g., tracheal tear, bleeding, pneumothorax, laryngeal nerve injury). Among the early complications, they survey the incidence of transplant necrosis and related mortality, further sequelae ensuing from subacute ischemia of the replaced organ and analyze in detail the questions which arise regarding anastomotic leakage. Firstly, they deal with those causative factors that influence the frequency of anastomotic insufficiency, such as the technical "know-how" of anastomosis making (e.g., one layer vs two layers; stapling or manual suture; interrupted or running suture), the way of replacement using whole stomach or tube-stomach and the consequences originating from the route of replacement (e.g., anterior or posterior mediastinal route). Incidence and management of chylothorax are also dealt with. While dealing with late complications, the authors give a detailed comment on anastomotic strictures and also other factors facilitating the development of late dysphagia, such as peptic stricture and tumor of the organ remnant. Finally, some cases successfully treated by surgery are presented (skin-tube formation in cases following transplant necrosis; abolition of a pharyngogastric anastomosis stricture using a free jejunal transplant and surgical solution of an anastomotic stricture from median sternotomy approach).
按时间顺序,并发症可分为术中并发症、早期并发症和晚期并发症。作者基于400多例食管手术及相关文献资料,依据此分类对并发症进行分析。关于术中并发症,他们仅探讨经裂孔食管切除术时发生的并发症(如气管撕裂、出血、气胸、喉返神经损伤)。在早期并发症方面,他们调查移植坏死的发生率及相关死亡率、移植器官亚急性缺血引发的后续后遗症,并详细分析吻合口漏相关问题。首先,他们探讨影响吻合口愈合不良发生率的致病因素,如吻合技术的“诀窍”(如单层缝合与双层缝合;吻合器吻合或手工缝合;间断缝合或连续缝合)、采用全胃或管状胃进行替代的方式以及替代路径产生的后果(如前纵隔或后纵隔路径)。还讨论了乳糜胸的发生率及处理方法。在讨论晚期并发症时,作者对吻合口狭窄以及导致晚期吞咽困难的其他因素(如消化性狭窄和器官残余肿瘤)进行了详细阐述。最后,介绍了一些通过手术成功治疗的病例(移植坏死病例中的皮管形成;使用游离空肠移植消除咽胃吻合口狭窄以及经正中胸骨切开术解决吻合口狭窄)。