Orringer M B
Ann Surg. 1984 Sep;200(3):282-8. doi: 10.1097/00000658-198409000-00005.
Transhiatal esophagectomy (THE) without thoracotomy was performed in 100 patients with carcinoma of the thoracic esophagus (7 upper, 45 mid, and 48 lower third). The esophagus was replaced with stomach (96) or colon (4). Intraoperative complications included pneumothorax requiring a chest tube(s) (63) and membranous tracheal tear (2). Blood loss averaged 880 ml. Postoperative complications included transient recurrent laryngeal nerve paresis (31), anastomotic leak (5), and chylothorax (2). There were no intraoperative deaths or re-explorations for postoperative bleeding. Six hospital deaths resulted from aspiration pneumonia (2), retroperitoneal or mediastinal abscess (2), pulmonary embolus (1), and respiratory insufficiency (1). Postoperative hospitalization averaged 14 days. Actuarial survival among the 94 operative survivors is 82% at 6 months, 52% at 12 months, 32% at 24 months, 22% at 36 months, and 17% at 48 months. Of the operative survivors, 15% have lived 2 years or more and 10% are clinically disease free. THE is safe, associated with a low morbidity, and achieves excellent palliation and survival at least as good as that reported in many series of transthoracic esophagectomies for esophageal carcinoma.
对100例胸段食管癌患者(7例为上段、45例为中段、48例为下段)实施了不开胸经裂孔食管切除术(THE)。食管置换采用胃(96例)或结肠(4例)。术中并发症包括需放置胸管的气胸(63例)和膜性气管撕裂(2例)。平均失血量为880毫升。术后并发症包括短暂性喉返神经麻痹(31例)、吻合口漏(5例)和乳糜胸(2例)。术中无死亡病例,术后也无需因出血而再次手术探查。6例患者死于医院,原因分别为吸入性肺炎(2例)、腹膜后或纵隔脓肿(2例)、肺栓塞(1例)和呼吸功能不全(1例)。术后平均住院时间为14天。94例手术幸存者的精算生存率在6个月时为82%,12个月时为52%,24个月时为32%,36个月时为22%,48个月时为17%。在手术幸存者中,15%存活了2年或更长时间,10%临床无病。THE手术安全,发病率低,能实现良好的姑息治疗效果,且生存率至少与许多经胸食管癌切除术系列报道的一样好。