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[周期性低钾性麻痹作为格雷夫斯病的表现:临床与电生理研究]

[Periodic hypokalemic paralysis as the manifestation of Graves' disease: clinical and electrophysiological study].

作者信息

Navarro V, Fournier E, Girard S, Delattre J Y, Eymard B

机构信息

Service de Neurologie, Hôpital de la Salpêtrière, Paris.

出版信息

Rev Neurol (Paris). 2000 Jan;156(1):59-61.

Abstract

A 30-year-old Vietnamese man experienced severe weakness of four limbs revealing hypokalaemia. Tachycardia and goiter allowed to diagnose a Graves' disease. Thyrotoxic hypokaliemic periodic paralysis is a rare complication of hyperthyroidism in western populations. Electromyogram performed after resolution of the paralysis episodes revealed marked abnormalities of the muscular excitability. Duration of compound muscular action potential was markedly increased after a brief exercise. This increase might indicate a delayed repolarization of muscle fibres.

摘要

一名30岁的越南男子出现四肢严重无力,检查发现低钾血症。心动过速和甲状腺肿提示诊断为格雷夫斯病。甲状腺毒症性低钾性周期性麻痹在西方人群中是甲状腺功能亢进症的一种罕见并发症。在麻痹发作缓解后进行的肌电图显示肌肉兴奋性明显异常。短暂运动后复合肌肉动作电位的持续时间明显增加。这种增加可能表明肌纤维复极化延迟。

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