[甲状腺毒症性低钾性周期性麻痹揭示一名男性白种人患有格雷夫斯病]
[Thyrotoxic hypokaliemic periodic paralysis revealing Graves' disease in a male Caucasian].
作者信息
Guilloton L, De Carvalho A, Quesnel L, Pasquet F, Mounier C, Drouet A
机构信息
Service de neurologie HIA Desgenettes, 108, boulevard Pinel, 69275 Lyon cedex 03, France.
出版信息
Rev Neurol (Paris). 2012 Feb;168(2):170-2. doi: 10.1016/j.neurol.2011.03.012. Epub 2011 Sep 1.
OBJECTIVES
Hypokaliemic thyrotoxic periodic paralysis (TPP) is an uncommon complication of hyperthyroidism. Mostly described among Asian patients, it is rare in other ethnic groups, in particular in Caucasian people.
CASE REPORT
We present the case of a Caucasian male admitted to our unit after several paretic episodes. Tachycardia, goiter and mild proptosis led to the diagnosis of Graves' disease.
CONCLUSION
Rare in the Caucasian population, TPP involves dysfunction of the NA-K-ATPase pump. Beta-blockers should be associated with medical or surgical treatment of hyperthyroidism.
目的
低钾性甲状腺毒症性周期性麻痹（TPP）是甲状腺功能亢进症的一种罕见并发症。主要在亚洲患者中被描述，在其他种族群体中罕见，尤其是在白种人中。
病例报告
我们报告一例白人男性患者，在经历几次麻痹发作后入住我院。心动过速、甲状腺肿大和轻度突眼导致格雷夫斯病的诊断。
结论
TPP在白种人群中罕见，涉及钠钾ATP酶泵功能障碍。β受体阻滞剂应与甲状腺功能亢进症的药物或手术治疗联合使用。
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