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47例牙瘤的临床病理研究

Clinicopathological studies of odontoma in 47 patients.

作者信息

Miki Y, Oda Y, Iwaya N, Hirota M, Yamada N, Aisaki K, Sato J, Ishii T, Iwanari S, Miyake M, Kudo I, Komiyama K

机构信息

Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry, Tokyo, Japan.

出版信息

J Oral Sci. 1999 Dec;41(4):173-6. doi: 10.2334/josnusd.41.173.

DOI:10.2334/josnusd.41.173
PMID:10693293
Abstract

A 14-year retrospective study was performed on 47 odontomas from the files of the 1st Department of Oral and Maxillofacial Surgery at Nihon University School of Dentistry. Fifty-seven percent of the patients were male and 42.6% were female. The age distribution was 8 to 48 years with a mean age of 22 +/- 9.0 years. There were no particular symptoms associated with the odontomas, and 63.8% of our patients had no symptoms. However, 12 patients complained of swelling and 9 of pain. The tumor was found in the maxilla in 42.6% and in the mandible in 57.4%. According to the WHO histological type classification, 53.2% of the tumors were classified as compound odontoma and 46.8% as complex odontoma. The size of the tumor ranged from 5 mm to 42 mm in diameter. The average complex odontoma was much bigger than the average compound odontoma. Ghost cells were found 11 cases in our series. In addition, odontogenic epithelium was found in 16 cases. Twenty seven patients had impacted teeth in association with odontoma and 24 of the 27 teeth were removed at the time of surgical enucleation of the tumor, while 3 cases were treated by orthodontically assisted eruption. There was no recurrence in any of the studied cases.

摘要

对日本大学牙科学院口腔颌面外科第一部存档的47例牙瘤进行了一项为期14年的回顾性研究。患者中57%为男性,42.6%为女性。年龄分布为8至48岁,平均年龄为22±9.0岁。牙瘤无特定症状,63.8%的患者无症状。然而,12例患者主诉肿胀,9例主诉疼痛。肿瘤位于上颌骨的占42.6%,位于下颌骨的占57.4%。根据世界卫生组织组织学类型分类,53.2%的肿瘤被归类为复合性牙瘤,46.8%为复杂性牙瘤。肿瘤大小直径范围为5毫米至42毫米。平均而言,复杂性牙瘤比复合性牙瘤大得多。本系列中有11例发现了牙釉质细胞。此外,16例发现了牙源性上皮。27例患者的牙瘤伴有阻生牙,其中24颗牙在肿瘤手术摘除时被拔除,3例采用正畸助萌治疗。所有研究病例均无复发。

相似文献

1
Clinicopathological studies of odontoma in 47 patients.47例牙瘤的临床病理研究
J Oral Sci. 1999 Dec;41(4):173-6. doi: 10.2334/josnusd.41.173.
2
Ameloblastic fibro-odontoma: report of two cases.成釉细胞纤维牙瘤:两例报告。
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[Composite odontoma and complex odontoma. Radiologic considerations].[组合性牙瘤与复杂性牙瘤。影像学考量]
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Ameloblastic Fibro-Odontoma: At the Crossroad Between "Developing Odontoma" and True Odontogenic Tumour.成釉纤维牙瘤:位于“发育性牙瘤”和真正牙源性肿瘤之间的十字路口。
Head Neck Pathol. 2021 Dec;15(4):1202-1211. doi: 10.1007/s12105-021-01332-6. Epub 2021 May 15.
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Ghost cell epithelium in odontomas.牙瘤中的影细胞上皮。
J Oral Pathol. 1975 Jul;4(1):27-30. doi: 10.1111/j.1600-0714.1975.tb01737.x.
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Complex and compound odontomas.复杂型和复合型牙瘤
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Odontoma: a clinicopathologic study of 81 cases.牙瘤:81例临床病理研究
J Formos Med Assoc. 2003 Dec;102(12):876-82.
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[Complex compound odontoma affecting the maxilla and mandible].[累及上颌骨和下颌骨的复合性牙瘤]
Stomatologiia (Mosk). 1980 Jun;59(3):64-5.
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Compound composite odontoma in primary dentition--a case report.乳牙列复合性复合牙瘤——病例报告
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A complex odontoma of the anterior maxilla associated with an erupting canine.上颌前部与萌出尖牙相关的复合性牙瘤。
BMJ Case Rep. 2013 Nov 12;2013:bcr2013200684. doi: 10.1136/bcr-2013-200684.

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Rare case of bilateral complex odontoma associated with mandibular bicuspids.罕见的双侧复合性牙瘤伴下颌双尖牙病例。
Dent Res J (Isfahan). 2018 May-Jun;15(3):220-223.
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Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation.出生后SOX2阳性牙干细胞中激活的WNT信号传导可驱动牙瘤形成。
Sci Rep. 2015 Sep 28;5:14479. doi: 10.1038/srep14479.
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Odontomas and supernumerary teeth: is there a common origin?牙瘤与多生牙:它们有共同的起源吗?
Int J Med Sci. 2014 Nov 12;11(12):1282-97. doi: 10.7150/ijms.10501. eCollection 2014.
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A rare case of odontome in a 65-year-old lady.一名65岁女性患牙瘤的罕见病例。
Natl J Maxillofac Surg. 2010 Jan;1(1):67-70. doi: 10.4103/0975-5950.69163.
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Two-stage surgical removal of large complex odontoma.
Oral Maxillofac Surg. 2010 Dec;14(4):247-52. doi: 10.1007/s10006-010-0206-0.
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A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: a case report and review of literature.一例与复合性牙瘤相关的色素沉着型钙化囊性牙源性肿瘤:病例报告及文献复习
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