牙瘤与多生牙：它们有共同的起源吗？
Odontomas and supernumerary teeth: is there a common origin?
作者信息
Pippi Roberto
机构信息
"Sapienza" University of Rome - Department of Odontostomatological and Maxillo Facial Sciences - Via Caserta 6, 00161 Rome - Italy.
出版信息
Int J Med Sci. 2014 Nov 12;11(12):1282-97. doi: 10.7150/ijms.10501. eCollection 2014.
Abstract
The aim of the present work is to analyze all scientific evidence to verify whether similarities supporting a unified explanation for odontomas and supernumerary teeth exist. A literature search was first conducted for epidemiologic studies indexed by PubMed, to verify their worldwide incidence. The analysis of the literature data shows some interesting similarities between odontomas and supernumerary teeth concerning their topographic distribution and pathologic manifestations. There is also some indication of common genetic and immuno-histochemical factors. Although from a nosological point of view, odontomas and supernumeraries are classified as distinct entities, they seem to be the expression of the same pathologic process, either malformative or hamartomatous.
摘要
本研究的目的是分析所有科学证据，以验证是否存在支持对牙瘤和多生牙进行统一解释的相似性。首先在PubMed索引的流行病学研究中进行文献检索，以核实它们在全球的发病率。文献数据分析显示，牙瘤和多生牙在其地形分布和病理表现方面存在一些有趣的相似之处。也有一些关于共同遗传和免疫组织化学因素的迹象。尽管从疾病分类学的角度来看，牙瘤和多生牙被归类为不同的实体，但它们似乎是同一病理过程的表现，无论是畸形还是错构瘤性的。
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