Nosik N N
Vopr Virusol. 2000 Jan-Feb;45(1):4-10.
The role of cytokines and chemokines in viral replication and antiviral immunity is discussed. Some viruses may have genes that mimic the host genes (cytokines or cytokine receptors) and their functioning may inhibit the synthesis or processing of cell proteins important for defense. Some of host cytokines may be involved in the pathogenesis of viral infection (HIV, herpes virus, cytomegalovirus, and some others).
本文讨论了细胞因子和趋化因子在病毒复制及抗病毒免疫中的作用。一些病毒可能拥有模仿宿主基因(细胞因子或细胞因子受体)的基因,其功能可能会抑制对防御至关重要的细胞蛋白质的合成或加工。一些宿主细胞因子可能参与病毒感染(如HIV、疱疹病毒、巨细胞病毒等)的发病机制。