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Malignant melanoma: death by image and ignorance, diagnosis by surgical excision and laboratory investigation.

作者信息

Magennis D P, Orchard G E

机构信息

Histopathology Department, Torbay Hospital, Torquay, England, UK.

出版信息

Br J Biomed Sci. 1999;56(2):134-44.

PMID:10695055
Abstract

Malignant melanoma is now one of the most common cancers in the western world. Across Europe, the rise in annual incidence is 4-7%. The criteria for clinical and histological diagnosis are well established; however, an elaborate range of laboratory investigations can provide valuable supplementary information in difficult cases. In this essay, we highlight the incidence and impact of malignant melanoma worldwide, and outline the range of laboratory investigations that can be performed and are so vital in the diagnosis of problematic cases.

摘要

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Comparison of immunohistochemical labelling of melanocyte differentiation antibodies melan-A, tyrosinase and HMB 45 with NKIC3 and S100 protein in the evaluation of benign naevi and malignant melanoma.在评估良性痣和恶性黑色素瘤时,黑色素细胞分化抗体melan-A、酪氨酸酶和HMB 45与NKIC3及S100蛋白的免疫组化标记比较
Histochem J. 2000 Aug;32(8):475-81. doi: 10.1023/a:1004192232357.