Moritake H, Taketomi A, Kamimura S, Ikuno Y, Seo Y, Fukuda T, Iguchi H, Okamura J
The Department of Pediatrics, National Kyushu Cancer Center, Fukuoka, Japan.
J Pediatr Hematol Oncol. 2000 Jan-Feb;22(1):78-80. doi: 10.1097/00043426-200001000-00015.
Renin-producing tumors of extrarenal origin are rare in children. An 8-year-old boy with hepatoblastoma and hypertension associated with a high plasma renin level is reported. After chemotherapy, the plasma renin level normalized and the hypertension spontaneously resolved. The patient underwent surgery, and a right trisegmentectomy of the liver and a partial resection of the second and third segments were performed. The tumor was as shown the source of renin by immunohistochemical study and reverse transcriptase-polymerase chain reaction.
肾外源性肾素瘤在儿童中罕见。本文报道了一名8岁患肝母细胞瘤并伴有高血压及高血浆肾素水平的男孩。化疗后，血浆肾素水平恢复正常，高血压自行缓解。患者接受了手术，行肝脏右三叶切除术及第二、三段部分切除术。免疫组化研究及逆转录酶-聚合酶链反应显示肿瘤为肾素来源。
