Vatistas N J, Snyder J R, Carlson G, Johnson B, Arthur R M, Thurmond M, Zhou H, Lloyd K L
Department of Surgical and Radiological Sciences, University of California, Davis 95616, USA.
Equine Vet J Suppl. 1999 Apr(29):34-9. doi: 10.1111/j.2042-3306.1999.tb05166.x.
Although gastric ulcers have been identified relatively frequently in racing Thoroughbreds, there have been no large scale studies to determine their effect on health and performance. Two hundred and two Thoroughbred horses in active race training were selected by the attending veterinarians for gastro-endoscopic examination. Images of the stomach mucosa were stored in a digitised format for subsequent evaluation. The number of ulcers and a score of severity were determined. Gastric ulceration of the squamous mucosa was identified in 82% of horses. Seventy-three (39%) horses displayed clinical signs consistent with gastric ulceration. Increasing Furr and Murray Score was associated with poor hair coat (P = 0.03), colic (P = 0.03), and increasing serum creatinine concentration (P = 0.029). There were no associations between haematology and serum biochemistry values (other than serum alkaline phosphatase concentration and serum creatinine concentration) and gastric ulceration. Our study confirmed the relatively high incidence of gastric ulceration in Thoroughbred horses involved in active race training. Gastric ulceration is a potential, but rare, cause of overt colic, but may produce more subtle detrimental effects on a horse's condition. It is concluded that the diagnosis of gastric ulceration should be based on an endoscopic examination of the stomach, although future studies are required to elucidate further the aetiology and clinical significance of gastric ulceration.
虽然在纯种赛马中胃溃疡已相对频繁地被发现，但尚未有大规模研究来确定其对健康和性能的影响。主治兽医挑选了202匹正在进行积极赛马训练的纯种马进行胃镜检查。胃黏膜图像以数字化形式存储以供后续评估。确定溃疡数量和严重程度评分。82%的马匹被发现有鳞状黏膜胃溃疡。73匹（39%）马表现出与胃溃疡相符的临床症状。弗尔和默里评分增加与被毛状况不佳（P = 0.03）、绞痛（P = 0.03）以及血清肌酐浓度升高（P = 0.029）相关。血液学和血清生化值（血清碱性磷酸酶浓度和血清肌酐浓度除外）与胃溃疡之间无关联。我们的研究证实了参与积极赛马训练的纯种马中胃溃疡的发病率相对较高。胃溃疡是明显绞痛的一个潜在但罕见的原因，但可能对马匹状况产生更细微的有害影响。结论是，胃溃疡的诊断应基于胃部的内镜检查，尽管未来需要进一步研究以阐明胃溃疡的病因和临床意义。
