在马术比赛期间应该允许使用奥美拉唑吗?

Should the use of omeprazole be allowed during equestrian competition?

作者信息

Campbell Madeleine L H, Sykes Benjamin W

机构信息

School of Veterinary Medicine and Science, University of Nottingham, Loughborough, UK.

School of Veterinary Sciences, Massey University, Palmerston North, New Zealand.

出版信息

Equine Vet J. 2025 May;57(3):555-562. doi: 10.1111/evj.14129. Epub 2024 Jul 12.

Abstract

BACKGROUND

Prioritising equine welfare, making evidenced-based policy, and consistent decision-making across sports are crucial to maintaining the social licence for equestrian sport. Regulations on the use of omeprazole during competition differ; all regulators argue that their rules prioritise welfare. This discrepancy is a matter of concern to the public and equestrian stakeholders.

OBJECTIVES

To apply Campbell's Ethical Framework for the use of Horses in Sport to the question: 'Should the use of omeprazole be allowed during equestrian competition?'

STUDY DESIGN

A desk-based ethico-legal study.

METHODS

Campbell's Ethical Framework for the Use of Horses in Sport was applied in a stepwise fashion: definition of the ethical question; analysis of the evidence base; consideration of stakeholders' interests; harm:benefit analysis; application of the three central tenets of the framework, and formulation of conclusions and recommendations.

RESULTS

Stakeholders in equine sports have a variety of (frequently conflicting) interests; all of them share an interest in optimising equine welfare. The incidence of EGUS in competition horses is high. Omeprazole is a cornerstone treatment. There are currently discrepancies in regulation about the use of omeprazole during competitions. Recent evidence suggests that withholding omeprazole treatment for two clear days before competition allows the recurrence of squamous EGUS, whereas withholding treatment on the day of competition only does not have that effect.

MAIN LIMITATIONS

The current state of scientific knowledge about the use of omeprazole in horses. The analysis did not consider possible health and thus welfare effects of the out-of-competition treatment with omeprazole.

CONCLUSIONS

Based on recent scientific evidence, if horses are being treated with omeprazole outside of competition then treatment on the day of competition should be permitted on welfare grounds. Revision of regulations around the use of omeprazole during competition by governing bodies is necessary to safeguard the ethical use of horses in sport.

摘要

背景

优先考虑马匹福利、制定基于证据的政策以及在各项体育赛事中进行一致的决策对于维持马术运动的社会许可至关重要。关于比赛期间使用奥美拉唑的规定各不相同;所有监管机构都认为他们的规则优先考虑福利。这种差异引起了公众和马术利益相关者的关注。

目的

将坎贝尔的《体育用马伦理框架》应用于问题:“马术比赛期间应允许使用奥美拉唑吗?”

研究设计

基于案头的伦理法律研究。

方法

逐步应用坎贝尔的《体育用马伦理框架》:定义伦理问题;分析证据基础;考虑利益相关者的利益;危害:益处分析;应用框架的三个核心原则,并得出结论和提出建议。

结果

马术运动中的利益相关者有各种(常常相互冲突的)利益;他们都对优化马匹福利有着共同利益。参赛马匹中食管胃十二指肠疾病(EGUS)的发病率很高。奥美拉唑是一种基础治疗药物。目前关于比赛期间使用奥美拉唑的规定存在差异。最近的证据表明,在比赛前连续两个整天停用奥美拉唑治疗会使鳞状EGUS复发,而仅在比赛当天停用治疗则没有这种效果。

主要局限性

关于在马匹中使用奥美拉唑的科学知识的现状。该分析未考虑奥美拉唑在非比赛期间治疗可能产生的健康以及因此对福利的影响。

结论

基于最近的科学证据,如果马匹在非比赛期间接受奥美拉唑治疗,那么出于福利考虑,应允许在比赛当天进行治疗。管理机构有必要修订关于比赛期间使用奥美拉唑的规定,以保障在体育活动中对马匹的道德使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ab/11982411/2b76c07a13b6/EVJ-57-555-g001.jpg

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