Miles A M, Anderson A S, Bernberg E L, Kent J, Rosenberger J K, Pope C R, Morgan R W
Delaware Agricultural Experiment Station, Department of Animal and Food Sciences, College of Agricultural Sciences, University of Delaware, Newark 19717-1303, USA.
Acta Virol. 1999 Apr-Jun;43(2-3):102-5.
We compared the RB1B and T. King (TK) serotype 1 isolates of Marek's disease virus (MDV) in vivo. Body and organ weights, mortality, and lesions indicated that the TK inoculum established early infection more efficiently than RB1B and did greater damage to the bursa of Fabricius and thymus. Subsequent studies showed that the TK inoculum that we used contained chicken infectious anemia virus (CIAV). Therefore, pathogenicity profiles shown here should be interpreted with the presence of CIAV contamination in the TK stock in mind.
我们在体内比较了马立克氏病病毒(MDV)的RB1B和T. King(TK)1型分离株。体重、器官重量、死亡率和病变表明,TK接种物比RB1B更有效地建立早期感染,并且对法氏囊和胸腺造成更大损害。随后的研究表明,我们使用的TK接种物含有鸡传染性贫血病毒(CIAV)。因此,此处所示的致病性概况应在考虑到TK毒株中存在CIAV污染的情况下进行解读。