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视网膜母细胞瘤患者的疑似孔源性视网膜脱离

Presumed rhegmatogenous retinal detachment in patients with retinoblastoma.

作者信息

Lim T H, Robertson D M

机构信息

Department of Ophthalmology, Mayo Medical Center, Rochester, Minnesota 55905, USA.

出版信息

Retina. 2000;20(1):22-7. doi: 10.1097/00006982-200001000-00004.

DOI:10.1097/00006982-200001000-00004
PMID:10696742
Abstract

PURPOSE

To review the characteristics, treatment, and outcome of presumed rhegmatogenous retinal detachment (RD) in patients with retinoblastoma.

METHODS

Descriptive consecutive case series study from 1970 to 1996.

RESULTS

Of 45 eyes with retinoblastoma that received various modalities of eye-sparing treatment and adequate follow-up, five developed presumed rhegmatogenous RD after treatment. All five eyes had previous treatment with external beam radiation, four of which also had been treated with cryotherapy. To minimize the potential spread of the malignancy intraoperatively, long disease-free intervals were ensured before scleral buckling surgeries were performed, and special care was taken during subretinal fluid drainage. The RDs were totally reattached in three eyes and partially reattached in the other two.

CONCLUSION

Presumed rhegmatogenous RD may occur after external beam radiation or cryotherapy for retinoblastoma. It poses special challenges in management.

摘要

目的

回顾视网膜母细胞瘤患者疑似孔源性视网膜脱离(RD)的特征、治疗方法及预后。

方法

对1970年至1996年的连续性病例进行描述性系列研究。

结果

45例接受了各种保眼治疗并进行了充分随访的视网膜母细胞瘤患者中,有5例在治疗后发生了疑似孔源性视网膜脱离。所有5只眼均曾接受过外照射放疗,其中4只眼还接受过冷冻治疗。为尽量减少术中恶性肿瘤的潜在扩散,在进行巩膜扣带手术前确保了较长的无病间期,并在视网膜下液引流时格外小心。3只眼的视网膜脱离完全复位,另外2只眼部分复位。

结论

视网膜母细胞瘤患者在接受外照射放疗或冷冻治疗后可能发生疑似孔源性视网膜脱离。这在治疗管理上带来了特殊挑战。

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