Waterhouse P J, Nunn J H, Whitworth J M
Department of Child Dental Health, The School of Dentistry, Newcastle upon Tyne.
Br Dent J. 2000 Jan 8;188(1):32-6. doi: 10.1038/sj.bdj.4800380.
To compare the clinical and radiological outcomes following two different, single visit vital pulp therapy techniques, in cariously exposed primary molar teeth.
A paediatric dental clinic within the Dental Hospital, Newcastle upon Tyne, UK.
Fifty two child patients were sequentially enrolled in the clinical investigation, 26 males and 26 females with an age range of 3.3-12.5 years. Primary molar teeth requiring vital pulp therapy were randomly allocated to either the formocresol group (F) or the calcium hydroxide group (C). The total number of teeth treated was 84.
Recruitment was on the basis of strict inclusion criteria. Coronal pulp amputation was prescribed only in teeth with vital, cariously exposed pulp tissue. Treatment was undertaken between October 1994 and December 1996. All cases were reviewed using predefined clinical and radiological criteria. The statistical tests used were logistic regression of a triple nested data structure, chi-squared analysis of equality of treatment and probability of success with relation to subject age.
Eighty-four cariously exposed primary molars required vital pulp therapy. Forty six (55%) teeth were included in the F group and 38 (45%) allocated to the C group. Five teeth were lost to follow-up, leaving 79 teeth: forty four (56%) in group F and 35 (44%) in group C. Eighty four percent (37/44) of teeth treated with formocresol and 77 percent (27/35) treated with calcium hydroxide were classed as clinically and radiographically successful at the cut-off date, December 1997, after a mean clinical review of 22.5 months (range 6.1-38.5 months) and a mean radiographic review of 18.9 months (range 1.3-36.9 months).
This investigation confirms the clinical efficacy of a one-fifth dilution of Buckley's Formocresol as an agent in pulp treatment of cariously exposed, vital primary molar teeth. However, calcium hydroxide in its pure, powder form is a clinically acceptable alternative when combined with strict selection criteria for this method of restorative care. There was a statistically insignificant difference in successful clinical and radiological outcome between the two treatment groups. Success was unrelated to the duration of time taken to achieve haemostasis and the presence or absence of bleeding after placement of the medicament.
比较两种不同的一次性活髓治疗技术用于治疗乳牙龋源性露髓后的临床和影像学结果。
英国泰恩河畔纽卡斯尔市牙科医院的儿科牙科诊所。
52名儿童患者按顺序纳入临床研究，其中男性26名，女性26名，年龄范围为3.3至12.5岁。需要进行活髓治疗的乳牙随机分为甲酚甲醛组（F）或氢氧化钙组（C）。治疗的牙齿总数为84颗。
根据严格的纳入标准进行招募。仅对牙髓活力正常且龋源性露髓的牙齿进行冠髓切断术。治疗于1994年10月至1996年12月期间进行。所有病例均按照预先定义的临床和影像学标准进行复查。所使用的统计检验包括三重嵌套数据结构的逻辑回归、治疗等效性的卡方分析以及与受试者年龄相关的成功概率分析。
84颗龋源性露髓的乳牙需要进行活髓治疗。46颗（55%）牙齿被纳入F组，38颗（45%）被分配到C组。5颗牙齿失访，剩余79颗牙齿：F组44颗（56%），C组35颗（44%）。在1997年12月截止日期时，甲酚甲醛治疗的牙齿中有84%（37/44）以及氢氧化钙治疗的牙齿中有77%（27/35）在临床和影像学上被判定为成功，平均临床复查时间为22.5个月（范围6.1 - 38.5个月），平均影像学复查时间为18.9个月（范围1.3 - 36.9个月）。
本研究证实了五分之一稀释度的巴克利氏甲酚甲醛作为龋源性露髓、牙髓活力正常的乳牙牙髓治疗药物的临床疗效。然而，当结合这种修复治疗方法的严格选择标准时，纯粉末状的氢氧化钙是一种临床上可接受的替代方法。两个治疗组在临床和影像学成功结果方面存在统计学上无显著差异。成功与否与实现止血所需的时间以及放置药物后是否出血无关。
