Ibricevic H, Al-Jame Q
Department of Pediatric Dentistry, Amiri Dental Centre, Kuwait.
Eur J Paediatr Dent. 2003 Mar;4(1):28-32.
The objective of this study was to compare the effects of ferric sulphate (FS) to that of the full strength of formocresol (Buckley's formula) (FC) as pulpotomy agents in primary human molar teeth 42-48 months after treatment. This was to assess the succeeding premolar teeth for decalcification, abnormal morphology or any other defect.
Seventy children, ranging in age from 3 to 6 years, mean 4.3 years, were treated for pulpotomy of primary molars. Ferric sulphate 15.5% solution (applied for 15 seconds for 84 teeth) and formocresol solution (5 minutes procedure for next the 80 teeth) were used as pulpotomy agents. In both groups, pulp stumps were covered with zinc oxide eugenol paste. Permanent restorations were, in most cases, stainless steel crowns and in some of them amalgams. Follow-up clinical assessments were every 3 months and the radiographic follow-up time was 6, 20 and 42-48 months after treatment.
The differences were statistically analyzed using the Chi square test.
These revealed 96.4% clinical success rate in the FS and 97.5% in the FC groups. Radiographic success rate in the FS group was 92.0%, while 94.6% in the FC group. No statistical significant differences were found between the radiographic assessment of the two pulpotomy agents.
Ferric sulphate showed similar clinical and radiographic success rate as a pulpotomy agent for primary molar teeth after long term evaluation period, compared with formocresol. Ferric sulphate, because of its lower toxicity, may become a replacement for formocresol in primary molar teeth.
本研究的目的是比较硫酸铁（FS）与全强度甲醛甲酚（巴克利配方）（FC）作为乳牙牙髓切断术药物在治疗后42 - 48个月对人乳磨牙的影响。这是为了评估后续前磨牙的脱钙、形态异常或任何其他缺陷情况。
70名年龄在3至6岁之间，平均年龄4.3岁的儿童接受了乳牙牙髓切断术治疗。使用15.5%的硫酸铁溶液（84颗牙齿应用15秒）和甲醛甲酚溶液（接下来的80颗牙齿采用5分钟操作流程）作为牙髓切断术药物。在两组中，牙髓残端均用氧化锌丁香油糊剂覆盖。在大多数情况下，永久性修复体为不锈钢冠，部分为汞合金。每3个月进行一次随访临床评估，治疗后6、20和42 - 48个月进行影像学随访。
采用卡方检验对差异进行统计学分析。
结果显示，FS组的临床成功率为96.4%，FC组为97.5%。FS组的影像学成功率为92.0%，FC组为94.6%。两种牙髓切断术药物的影像学评估之间未发现统计学显著差异。
经过长期评估期，硫酸铁作为乳牙牙髓切断术药物，与甲醛甲酚相比，显示出相似的临床和影像学成功率。由于其毒性较低，硫酸铁可能成为乳牙牙髓切断术中甲醛甲酚的替代品。
