Thomson W M, Chalmers J M, Spencer A J, Williams S M
Department of Oral Health, University of Otago, Dunedin, New Zealand.
Community Dent Health. 1999 Mar;16(1):12-7.
To develop a valid multi-item method of measuring the symptoms of xerostomia which includes the wide range of xerostomia symptoms in a single quantitative measure.
A combination of qualitative and quantitative approaches.
A cohort study in South Australia.
Older people aged 65 years or more who were taking part in the South Australian Dental Longitudinal Study.
Xerostomia symptoms were evaluated using a multi-item inventory format and, for comparison purposes, a standard single dry-mouth question. Resting whole-salivary flow rate was estimated using the 'spit' method.
Xerostomia and flow-rate data were available for 636 individuals. Factor analysis revealed the presence of a discrete xerostomia dimension, represented by 11 items whose responses were summated to give a single Xerostomia Inventory (XI) scale score. This had a very low correlation with resting flow rate but a much stronger, positive correlation with the standard dry-mouth question responses.
The XI shows adequate content and concurrent validity, and appears to be a promising advance on previous approaches to xerostomia symptomatology although further testing is required.
开发一种有效的多项目方法来测量口干症状，该方法能在单一量化测量中涵盖广泛的口干症状。
定性与定量方法相结合。
南澳大利亚的一项队列研究。
参与南澳大利亚牙科纵向研究的65岁及以上老年人。
采用多项目问卷形式评估口干症状，并为作比较使用一个标准的单一口干问题。使用“吐唾沫”法估算静息全唾液流速。
有636名个体的口干及流速数据。因子分析显示存在一个独立的口干维度，由11个项目表示，这些项目的回答经汇总得出一个单一的口干量表（XI）得分。该得分与静息流速的相关性非常低，但与标准口干问题回答的正相关性更强。
XI显示出足够的内容效度和同时效度，尽管还需要进一步测试，但似乎是在既往口干症状学研究方法基础上的一个有前景的进展。
