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[人体抗风湿(抗炎)药物的评价标准]

[Criteria for the evaluation of the antirheumatic (antiinflammatory) drugs in man].

作者信息

Delbarre F, Mery C, Nakache J P, de Géry A, Chastang C

出版信息

C R Acad Hebd Seances Acad Sci D. 1978 Oct 23;287(10):967-70.

PMID:106982
Abstract

Comparison of 5 antiinflammatory drugs and placebo in a double blind, short term, cross-over trial conducted in patients suffering from rheumatoid arthritis. 15 measurements were used and studied. With classical unidimensional statistical tests it was not possible to discriminate active drugs between them. Multidimensional analysis (correspondance analysis and discriminant analysis) are more sensitive and allow us to distinguish active drugs with only 11 criterion.

摘要

在一项针对类风湿性关节炎患者进行的双盲、短期、交叉试验中,对5种抗炎药物与安慰剂进行比较。使用并研究了15项测量指标。采用经典的单维统计检验无法区分这些活性药物。多维分析(对应分析和判别分析)更为灵敏,仅用11项标准就能让我们区分活性药物。

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