• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Advice on hair and scalp care during cranial radiotherapy: a prospective randomized trial.

作者信息

Westbury C, Hines F, Hawkes E, Ashley S, Brada M

机构信息

Neuro-oncology Unit, The Royal Marsden NHS Trust, Downs Road, Sutton, UK.

出版信息

Radiother Oncol. 2000 Feb;54(2):109-16. doi: 10.1016/s0167-8140(99)00146-2.

DOI:10.1016/s0167-8140(99)00146-2
PMID:10699472
Abstract

BACKGROUND

The advice on hair washing during brain irradiation is aimed at minimizing radiation induced skin toxicity. We performed a prospective randomized trial to assess the effect of advice on scalp care on the local skin reaction in patients undergoing cranial radiotherapy.

METHODS

One hundred and nine patients undergoing cranial radiotherapy were randomized into two groups. Patients in group 1 were advised not to wash hair during treatment and patients in group 2 to maintain normal pattern of hair washing. They were assessed weekly over a period of 10 weeks from the start of treatment. Symptoms of pain and itching were recorded using a modified RTOG/EORTC acute skin reaction scoring system and skin reaction was assessed clinically using erythema/desquamation score. The frequency of hair washing and the distress of changing the practice of normal hygiene were recorded on a diary card. Skin reaction scores were compared as a summary measure using area under the curve per week (AUC/week) and median scores, and the differences between groups were assessed by means of the t-test.

RESULTS

One hundred and nine patients commencing cranial radiotherapy according to standard protocol were randomized into the trial (group 1, 55 patients; group 2, 54 patients). Patients asked to restrict hair washing, washed at a lower average frequency. There were no significant differences between scores of skin reaction in the two groups for each of the variables measured.

CONCLUSIONS

The practice of normal hair washing is not associated with increased severity of adverse skin reaction. As a request to change the pattern of normal hygiene may cause distress, the current advice should be to maintain normal hair washing during cranial radiotherapy.

摘要

相似文献

1
Advice on hair and scalp care during cranial radiotherapy: a prospective randomized trial.
Radiother Oncol. 2000 Feb;54(2):109-16. doi: 10.1016/s0167-8140(99)00146-2.
2
The impact of skin washing with water and soap during breast irradiation: a randomized study.乳腺癌放疗期间用水和肥皂清洗皮肤的影响:一项随机研究。
Radiother Oncol. 2001 Mar;58(3):333-9. doi: 10.1016/s0167-8140(00)00322-4.
3
A double-blind, randomized, prospective trial to evaluate topical vitamin C solution for the prevention of radiation dermatitis. CNS Cancer Consortium.
Int J Radiat Oncol Biol Phys. 1993 Jun 15;26(3):413-6. doi: 10.1016/0360-3016(93)90958-x.
4
Physiological and microbiological verification of the benefit of hair washing in patients with skin conditions of the scalp.头皮皮肤病患者洗发益处的生理及微生物学验证。
J Cosmet Dermatol. 2016 Dec;15(4):e1-e8. doi: 10.1111/jocd.12228. Epub 2016 May 26.
5
Prophylactic beclomethasone spray to the skin during postoperative radiotherapy of carcinoma breast: a prospective randomized study.乳腺癌术后放疗期间对皮肤预防性使用倍氯米松喷雾剂:一项前瞻性随机研究。
Indian J Cancer. 2006 Oct-Dec;43(4):180-4. doi: 10.4103/0019-509x.29424.
6
Thêta-Cream versus Bepanthol lotion in breast cancer patients under radiotherapy. A new prophylactic agent in skin care?乳腺癌放疗患者使用θ乳膏与拜耳多护肤软膏的对比研究。一种皮肤护理新的预防剂?
Strahlenther Onkol. 2004 May;180(5):315-22. doi: 10.1007/s00066-004-1174-9.
7
Skin reactions during radiotherapy for breast cancer: the use and impact of topical agents and dressings.乳腺癌放疗期间的皮肤反应:局部用药和敷料的使用及影响
Eur J Cancer Care (Engl). 1999 Sep;8(3):143-53. doi: 10.1046/j.1365-2354.1999.00153.x.
8
Scalp dose analysis for transient and permanent alopecia following conventional cranial irradiation using Image Guided Radiotherapy (IGRT): A prospective study.常规颅照射后应用图像引导放疗(IGRT)导致的短暂性和永久性脱发的头皮剂量分析:一项前瞻性研究。
PLoS One. 2024 Oct 10;19(10):e0311855. doi: 10.1371/journal.pone.0311855. eCollection 2024.
9
Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy.海马体保留全脑放射治疗防脱发效果的剂量学分析
Radiat Oncol. 2015 Nov 26;10:245. doi: 10.1186/s13014-015-0555-9.
10
Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial.水剂或硫糖铝乳膏会影响放射性红斑皮肤反应的严重程度吗?一项随机对照试验。
Radiother Oncol. 2004 Nov;73(2):153-62. doi: 10.1016/j.radonc.2004.07.032.

引用本文的文献

1
Systematic review of the tools and outcomes for the assessment of acute radiation dermatitis severity.急性放射性皮炎严重程度评估工具及结果的系统评价
Clin Transl Radiat Oncol. 2025 May 9;53:100977. doi: 10.1016/j.ctro.2025.100977. eCollection 2025 Jul.
2
Radiation-induced skin injury in the head and neck region: pathogenesis, clinics, prevention, treatment considerations and proposal for management algorithm.头颈部区域的放射性皮肤损伤:发病机制、临床症状、预防、治疗考量及管理算法建议
Rep Pract Oncol Radiother. 2024 Jul 22;29(3):373-390. doi: 10.5603/rpor.100775. eCollection 2024.
3
The validity of over-the-counter skin, hair, and nail recommendations for adult patients with cancer: A systematic review.
非处方皮肤、头发和指甲产品推荐对成年癌症患者的有效性:一项系统评价。
Support Care Cancer. 2024 Aug 8;32(9):577. doi: 10.1007/s00520-024-08735-5.
4
Efficacy of Supportive Care for Radiodermatitis in Patients with Head and Neck Cancer: Supplementary Analysis of an Exploratory Phase II Trial.头颈部癌患者放射性皮炎的支持性护理疗效:一项探索性II期试验的补充分析
J Pers Med. 2023 Sep 16;13(9):1387. doi: 10.3390/jpm13091387.
5
Risk assessment, surveillance, and nonpharmaceutical prevention of acute radiation dermatitis: results of a multicentric survey among the German-speaking radiation oncology community.急性放射性皮炎的风险评估、监测和非药物预防:德语放疗界的一项多中心调查结果。
Strahlenther Onkol. 2023 Oct;199(10):891-900. doi: 10.1007/s00066-023-02074-w. Epub 2023 Apr 26.
6
Prevention of radiation dermatitis with skin hygiene and washing: a systematic review and meta-analysis.预防放射性皮炎的皮肤卫生与清洗:系统评价和荟萃分析。
Support Care Cancer. 2023 Apr 22;31(5):294. doi: 10.1007/s00520-023-07720-8.
7
What is the appropriate skin cleaning method for nasopharyngeal cancer radiotherapy patients? A randomized controlled trial.鼻咽癌放疗患者适宜的皮肤清洁方法是什么?一项随机对照试验。
Support Care Cancer. 2022 May;30(5):3875-3883. doi: 10.1007/s00520-022-06835-8. Epub 2022 Jan 17.
8
Skin toxicities associated with tumor treating fields: case based review.与肿瘤治疗电场相关的皮肤毒性:病例分析。
J Neurooncol. 2017 Dec;135(3):593-599. doi: 10.1007/s11060-017-2612-8. Epub 2017 Aug 28.
9
A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions.局部使用金盏花预防和治疗放疗引起的皮肤反应的综述
Antioxidants (Basel). 2015 Apr 23;4(2):293-303. doi: 10.3390/antiox4020293.
10
Quantitative monitoring of radiation induced skin toxicities in nude mice using optical biomarkers measured from diffuse optical reflectance spectroscopy.利用漫反射光谱法测量的光学生物标志物对裸鼠辐射诱导的皮肤毒性进行定量监测。
Biomed Opt Express. 2014 Apr 1;5(5):1309-20. doi: 10.1364/BOE.5.001309. eCollection 2014 May 1.