斑点印迹试验在哥伦比亚和秘鲁伤寒热患者中诊断肠热症沙门氏菌血清型伤寒所致肠热症的临床应用
Clinical application of a dot blot test for diagnosis of enteric fever due to Salmonella enterica serovar typhi in patients with typhoid fever from Colombia and Peru.
作者信息
Cardona-Castro N, Gotuzzo E, Rodriguez M, Guerra H
机构信息
Instituto Columbiano de Medicina Tropical, AA 52162 Medellín, Colombia.
出版信息
Clin Diagn Lab Immunol. 2000 Mar;7(2):312-3. doi: 10.1128/CDLI.7.2.312-313.2000.
Abstract
Clinical application of a dot blot test to detect immunoglobulin G (IgG) (88% sensitivity and specificity) and IgM (12.1% sensitivity and 97% specificity) against flagellar antigen from Salmonella enterica serovar Typhi was performed in Peruvian and Colombian patients with typhoid fever. This test can be used as a good predictor of serovar Typhi infection in regions lacking laboratory facilities and in field studies.
摘要
针对秘鲁和哥伦比亚伤寒热患者，开展了一项斑点印迹试验的临床应用，以检测抗伤寒沙门氏菌鞭毛抗原的免疫球蛋白G（IgG）（敏感性和特异性均为88%）和免疫球蛋白M（敏感性为12.1%，特异性为97%）。在缺乏实验室设施的地区和现场研究中，该试验可作为伤寒血清型感染的良好预测指标。
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