Camitta B M
Midwest Children's Cancer Center, Department of Pediatrics, Medical College of Wisconsin and the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.
Acta Haematol. 2000;103(1):16-8. doi: 10.1159/000040999.
Treatment with immune suppression and bone marrow transplantation has improved the response rates and survival of patients with aplastic anemia. Measurement of response requires that common endpoints be recorded at specific times. There has been no agreement on such parameters for patients with aplastic anemia. In this paper issues related to measurement of response are reviewed and criteria for response are proposed. Adoption of uniform criteria would facilitate comparisons of treatment efficacy.
免疫抑制和骨髓移植治疗已提高了再生障碍性贫血患者的缓解率和生存率。疗效评估要求在特定时间记录常见的终点指标。对于再生障碍性贫血患者的此类参数尚无统一意见。本文回顾了与疗效评估相关的问题并提出了缓解标准。采用统一标准将有助于比较治疗效果。
