Solomon A C, Baloch Z W, Salhany K E, Mandel S, Weber R S, LiVolsi V A
Department of Pathology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.
Arch Pathol Lab Med. 2000 Mar;124(3):446-9. doi: 10.5858/2000-124-0446-TSMCWE.
We present the clinical and pathologic findings of a case of sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid in a 39-year-old woman. This particular case is notable because it initially presented as a cervical lymph node metastasis, and the initial clinical and histologic impression was Hodgkin disease, nodular sclerosis type. Sclerosing mucoepidermoid carcinoma with eosinophilia is a differentiated malignant neoplasm of the thyroid that can be confused with anaplastic carcinoma, medullary carcinoma, squamous cell carcinoma, or, as in this case, Hodgkin disease. A correct diagnosis of sclerosing mucoepidermoid carcinoma with eosinophilia involves awareness of this entity and appropriate immunohistochemical analysis. In this article, we briefly review the literature and stress the histologic and cytologic findings characteristic of sclerosing mucoepidermoid with eosinophilia of the thyroid.
我们报告了一名39岁女性甲状腺硬化性黏液表皮样癌伴嗜酸性粒细胞增多症的临床和病理表现。该特殊病例值得关注，因为它最初表现为颈部淋巴结转移，最初的临床和组织学印象是结节硬化型霍奇金病。甲状腺硬化性黏液表皮样癌伴嗜酸性粒细胞增多症是一种分化型甲状腺恶性肿瘤，可与未分化癌、髓样癌、鳞状细胞癌混淆，或如本病例一样与霍奇金病混淆。正确诊断甲状腺硬化性黏液表皮样癌伴嗜酸性粒细胞增多症需要认识到这一实体并进行适当的免疫组化分析。在本文中，我们简要回顾了文献，并强调了甲状腺硬化性黏液表皮样癌伴嗜酸性粒细胞增多症的组织学和细胞学特征。
