Galin M A, Chowchuvech E, Turkish L
Trans Ophthalmol Soc U K (1962). 1976 Apr;96(1):166-7.
Discs of polymethylmethacrylate containing 0-5 per cent. unpolymerized monomer were heated to create increasing concentrations of unpolymerized fragments up to 3-7 per cent. These fragments were then studied in tissue culture and in the anterior chambers of rabbits. No toxicity was evident in culture nor was there a difference in anterior segment response to the discs containing various concentrations of monomer. It would appear that the inflammatory response after implantation is predominantly mechanical in origin.
含有0%至5%未聚合单体的聚甲基丙烯酸甲酯圆盘被加热,以产生高达3%至7%的未聚合碎片浓度。然后在组织培养和兔前房中对这些碎片进行研究。在培养中未发现明显毒性,并且含有不同浓度单体的圆盘对眼前节的反应也没有差异。看来植入后的炎症反应主要源于机械因素。