Sevastikoglou J A, Lemperg R, Larsson S E, Mattsson S
Acta Chir Scand Suppl. 1976;467:26-30.
The chemical composition, i.e. ash and calcium contents and organic, hydroxyproline, and hexosamine contents of the acetone-dried diaphyseal cortical bone powder of the tibias and the femurs, was studied in adult rats after a) below-knee amputation and b) immobilisation of the one hind leg in a plaster cast. There were no significant differences in the chemical composition of the chemical composition of the bones of the treated extremity as compared with the corresponding bones from the non-treated control leg, either at different times after the amputation and immobilisation, respectively, or when all obtained values from each bone were tested together. The percentage hydroxyproline content of the tibia was found to be significantly higher than that of the femur in both extremities, both in the amputation and in the immobilisation experiment. The pro mille hexosamine content of the tibia, on the other hand, was significantly lower than that of the femur in both extremeities in the immobilisation experiment.
研究了成年大鼠在以下两种情况下，胫骨和股骨经丙酮干燥的骨干皮质骨粉的化学成分，即灰分、钙含量以及有机成分、羟脯氨酸和己糖胺含量：a）膝下截肢后；b）用石膏固定一条后腿。无论是在截肢和固定后的不同时间，还是将每根骨头的所有测量值一起进行测试时，与未处理的对照腿相应骨头相比，处理过的肢体骨头的化学成分均无显著差异。在截肢和固定实验中，发现双侧胫骨的羟脯氨酸含量百分比均显著高于股骨。另一方面，在固定实验中，双侧胫骨的己糖胺含量千分率均显著低于股骨。
