Baciu C C, Muncaciu S, Dumitrescu D
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1989 Sep-Oct;38(5):381-6.
A total of 16 cases only have been reported in the world specialized literature. This is a new case, of a patient aged 20 years, a male working in the metallurgical industry. This is the first case reported in our country. Clinically the patient presented a painful global swelling of the median third of the clavicula on the left side. Biological constant were normal. Radiographic investigations revealed an increase in volume and a condensation of the median part of the clavicula, and scintigraphical studies revealed an intense incorporation of the radioisotope. Histopathologic studies showed lamellar and spongious bone tissue, with a normal trabecular structure, although considerably thickened. Data for the differential diagnosis are presented, and in the first place those concerning intra-sterno-clavicular hyperostosis, sterno-costo-clavicular arthrosis, chronic subacute osteitis, avascular necrosis of the clavicular epiphysis (Friedrich disease), and Tietze syndrome. The etiopathogenesis of this rare benign clinico-radiologic entity remains unknown.
世界专业文献中仅报道了16例。这是一例新病例，患者为20岁男性，从事冶金行业。这是我国报道的首例病例。临床上，患者左侧锁骨中段出现疼痛性整体肿胀。生物学指标正常。影像学检查显示锁骨中段体积增大且密度增高，闪烁扫描研究显示放射性同位素摄取强烈。组织病理学研究显示为板层状和海绵状骨组织，小梁结构正常，尽管明显增厚。文中给出了鉴别诊断数据，首先是关于胸锁关节内骨质增生、胸锁关节骨关节炎、慢性亚急性骨炎、锁骨骨骺缺血性坏死（弗里德里希病）和蒂策综合征的数据。这种罕见的良性临床-放射学实体的病因发病机制尚不清楚。
